| Description |
1 online resource (652 pages) |
|
text txt rdacontent |
|
computer c rdamedia |
|
online resource cr rdacarrier |
| Note |
Print version record. |
| Summary |
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Timely and critical reviews of important topics in medicinal chemistry. |
| Contents |
Personal essays. Reflections on medicinal chemistry at Merck, West Point / Paul S. Anderson -- My path in seeking new medicines / Peter R. Bernstein -- Tales of drug discovery / M. Ross Johnson -- pt. 1. Central nervous system diseases. Recent developments in targeting neuroinflammationn in disease / Allen T. Hopper [and others] -- Secretase inhibitors and modulators as a disease-modifying approach against Alzheimer's Disease -- mGluR2 activators and mGluR5 blockers advancing in the clinic for major CNS disorders / Sylvain Célanire [and others] -- NMDA antagonists of GluN2B subtype and modulators of GluN2A, GluN2C, and GluN2D suybtypes -- recent results and developments / Kamalesh B. Ruppa, Dalton King, and Richard E. Olson -- Recent advances in the developmentof PET and SPECT tracers for brain imaging / Lei Zhang and Anabella Villalobos -- pt. 2. Cardiovascular and metabolic diseases. Case history : Eliquis (Apixaban), a potent and selective inhibitor of coagulation factor Xa for the prevention and treatment of thrombotic diseases / Donald M.p. Pinto [and others] -- AMPK activation in health and disease / Iyassu K. Sebhat and Robert W. Myers -- Type-2 diabetes and associated comorbidities as an inflammatory syndrome / Juan C. Jaen, Jay P. Powers, and Tim Sullivan -- Beyond PPARs and metformin : new insulin sensitizers for the treatment of type 2 diabetes / Philip A. Carpino and David Hepworth -- pt. 3. Inflammation pulmonary GI. Recent advances in the discovery and development of sphingosine-1-phosphate-1 receptor agonists / Alaric J. Dyckman -- Bifunctional compounds for the treatment of COPD / Gary Phillips and Michael Salmon -- Inflammatory targets for the treatment of atherosclerosis / Robert O. Hughes, Alessandra Bartolozzi, and Hidenori Takahashi. |
| Subject |
Pharmaceutical chemistry -- Periodicals.
|
|
Clinical chemistry.
|
|
Pharmaceutical chemistry.
|
|
Chemistry, Clinical |
|
Chemistry, Pharmaceutical |
|
Chimie pharmaceutique -- Périodiques.
|
|
Chimie clinique.
|
|
Chimie pharmaceutique.
|
|
MEDICAL -- Drug Guides.
|
|
MEDICAL -- Nursing -- Pharmacology.
|
|
MEDICAL -- Pharmacology.
|
|
MEDICAL -- Pharmacy.
|
|
Clinical chemistry
|
|
Pharmaceutical chemistry
|
| Genre/Form |
Periodical |
|
periodicals.
|
|
Periodicals
|
|
Periodicals.
|
|
Périodiques.
|
| Added Author |
Desai, Manoj C.
|
|
American Chemical Society. Division of Medicinal Chemistry.
|
| Other Form: |
Print version: Annual reports in medicinal chemistry. Volume 47. Oxford : Academic, 2012 9780123964922 (OCoLC)806198309 |
| ISBN |
9780123972149 (electronic bk.) |
|
0123972140 (electronic bk.) |
|
9780123964922 |
|
012396492X |
| Standard No. |
AU@ 000051564425 |
|
CHBIS 010356004 |
|
CHVBK 329770047 |
|
DEBSZ 405345623 |
|
AU@ 000055847688 |
|
