| Description |
1 online resource |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Note |
Includes index. |
| Contents |
Front Cover -- Organofluorine Chemistry -- Copyright Page -- Contents -- Preface -- 1 Nucleophilic reactions in the synthesis of organofluorine compounds -- 1.1 Introduction -- 1.2 Reagents for nucleophilic fluorinations -- 1.3 Nucleophilic deoxyfluorination -- 1.4 Nucleophilic fluorination of pyridines and diazines -- 1.5 Nucleophilic gem-difluorination of carbonyl compounds -- 1.6 Nucleophilic fluoroalkylations -- 1.6.1 Nucleophilic difluoromethylation of aldehydes -- 1.6.2 Ruppert-Prakash reagent (CF3SiMe3) for trifluoromethylation -- 1.6.2.1 Enantioselective trifluoromethylation |
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1.6.2.2 Synthesis of trifluoromethyl ketones -- 1.6.2.3 Trifluoromethylation of imines -- 1.6.3 Fluoroacetone hydrates for the nucleophilic fluoroalkylations -- 1.6.4 Trifuoromethylations using fluoroform (CHF3) -- 1.6.5 Borazine-mediated trifluoromethylation and difluoroalkylation -- 1.6.6 N-Trifluoromethylation of amines -- 1.6.7 Tetrakis(dimethylamino)ethylene-mediated fluoroalkylations -- 1.6.7.1 Trifluoromethylation of acyl chlorides -- 1.6.7.2 Synthesis of gem-(difluoromethyl)thioethers -- 1.7 Nucleophilic trifluoromethylthiolation -- 1.8 Trifluoromethoxylations |
| Summary |
Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of small molecule compounds in drug discovery, positron emission tomography, and fluorinated polymers in solar cells. This book is of use to scientists working in the interdisciplinary areas, such as chemical, biochemical, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students interested in organofluorine chemistry. Provides modern synthetic methods and reactions of organofluorine compounds Incorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals, and polymeric materials Features emerging "hot" topics, such as late-stage fluorinations and drug discovery |
| Subject |
Organofluorine compounds.
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Composés organiques fluorés.
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Organofluorine compounds
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| Other Form: |
Print version: 9780128132876 |
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Print version: 0128132868 9780128132869 (OCoLC)1111975436 |
| ISBN |
9780128132876 (electronic bk.) |
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0128132876 (electronic bk.) |
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0128132868 |
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9780128132869 |
| Standard No. |
AU@ 000067001785 |
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AU@ 000068653475 |
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