| Edition |
First edition. |
| Description |
1 online resource |
|
text txt rdacontent |
|
computer c rdamedia |
|
online resource cr rdacarrier |
| Note |
Online resource; title from PDF title page (EBSCO, viewed February 9, 2016) |
| Bibliography |
Includes bibliographical references and indexes. |
| Contents |
Front Cover; The Alkaloids Chemistry and Biology; Copyright; DEDICATION; Contents; CONTRIBUTORS; PREFACE; One -- Sarpagan-Ajmalan-Type Indoles: Biosynthesis, Structural Biology, and Chemo-Enzymatic Significance; 1. INTRODUCTION; 2. RAUVOLFIA ALKALOIDS-SOURCES, THERAPEUTIC VALUE, AND ENZYME DETECTION; 2.1 Choosing an Efficient Biological System; 2.2 The Alkaloid Pattern of Rauvolfia Cell Cultures; 2.3 Chemical Syntheses of Biosynthetic Intermediates; 2.4 Detection of Enzyme Activities and Enzyme Purification; 3. ENZYMES OF THE AJMALINE PATHWAY (AP); 3.1 Strictosidine Synthase (STR) |
|
4.3.2 Raucaffricine Glucosidase (RG)4.3.3 Perakine Reductase (PR); 4.4 Side Routes Beyond Perakine and Raucaffrinoline; 4.5 The Route Beyond Ajmaline; 4.5.1 Side Route: From Ajmaline to Raumaclines; 4.5.2 Biosynthesis of Raumaclines; 4.5.3 Dialdehyde Reductase; 5. MONITORING BIOCONVERSIONS BY IN VIVO NMR; 6. CHEMO-ENZYMATIC APPROACHES; 6.1 From Single to Bunch-From Strictosidine Synthase (STR) to Novel Alkaloids; 6.2 Chemo-Enzymatic Application of Raucaffricine Glucosidase (RG); 7. SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Two -- Sarpagine and Related Alkaloids; 1. INTRODUCTION; 1.1 Classification |
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1.2 Biosynthesis2. OCCURRENCE; 2.1 Recently Isolated Sarpagine-Related Indole Alkaloids; 3. SPECTROSCOPY; 3.1 1H NMR Spectroscopy; 3.2 13C NMR Spectroscopy; 4. PHARMACOLOGY; 5. SYNTHESIS; 5.1 The Asymmetric Pictet-Spengler Reaction; 5.2 Synthesis of Sarpagine/Macroline-Related Indole Alkaloids; 5.2.1 The Enantiospecific Total Synthesis of (+)-Vellosimine (161) by Wang; 5.2.2 A Biomimetic Total Synthesis of (+)-Na-Methylvellosimine (168) by Martin et al.; 5.2.3 Synthesis of (+)-Na-Methyl-16-Epi-Pericyclivine (180) |
| Subject |
Alkaloids.
|
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Alcaloďdes.
|
|
SCIENCE / Life Sciences / Biochemistry
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Alkaloids
|
| Added Author |
Knölker, Hans-Joachim, editor.
|
| ISBN |
9780128048351 electronic bk. |
|
0128048352 electronic bk. |
|
9780128046821 |
| Standard No. |
GBVCP 879390700 |
|
