| Description |
1 online resource |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Micro & nano technologies |
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Micro & nano technologies.
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| Bibliography |
Includes bibliographical references and index. |
| Note |
Vendor-supplied metadata. |
| Contents |
Front Cover; Drug Delivery Nanosystems for Biomedical Applications; Copyright; Contents; Contributors; Chapter 1: Drug delivery nanosystems-An introduction; 1.1 Foreword; 1.2 Different Forms of Drug Delivery Vehicles; 1.2.1 Colloidal Nanoparticles and Nanocapsules; 1.2.2 Nonspherical and Inorganic Nanoparticles; 1.2.3 Polymeric Micelles and Other Nanoparticles; 1.3 Classification of Drug Delivery Nanosystems; 1.4 Versatality to the Target Site; 1.5 Perspectives; References; Chapter 2: Blood compatibility of nanomaterials; 2.1 Introduction; 2.2 Blood Compatibility: Background |
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2.3 Macro-materials2.4 Nanomaterials; 2.4.1 Platelet Adhesion/Aggregation, Plasma Coagulation, Complement Activation, Hemolysis; 2.4.2 Protein Adsorption: The Corona; Acknowledgments; References; Chapter 3: Safety and toxicity concerns of nanosystems; 3.1 Introduction; 3.2 Nanoparticle Exposure; 3.2.1 Occupational Exposure; 3.2.2 Environmental Exposure; 3.2.3 Consumer Exposure; 3.3 Routes of Exposures; 3.3.1 Inhalation; 3.3.2 Transdermal Absorption; 3.3.3 Ingestion; 3.3.4 Injection/Parenteral Administration; 3.4 Bio-Nano Interactions-Cellular and Molecular Levels; 3.5 Nanoparticle Uptake |
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3.6 Protein Corona3.7 Membrane Integrity; 3.8 Cytoskeletal Arrangement; 3.9 Organellar Dysfunction; 3.10 Apoptosis; 3.11 Reactive Oxygen Species and Oxidative Stress; 3.12 Genotoxicity; 3.13 Conclusion; Acknowledgments; References; Chapter 4: Pharmaceutical perspectives of selection criteria and toxicity profiling of nanotheranostic agents; 4.1 Introduction; 4.2 Critical Gap That Nanotheranostics Fills in Therapeutics; 4.3 Features and Concerns of Nanoparticle for Nanotheranostic Design |
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4.3.1 Structural and Electronic Properties of Nanoparticles at Nanoscale and Its Influence on Biological Functions4.3.2 Macroscale Dispersibility Properties of Nanoparticles Influencing the Biological Functions; 4.3.3 Dissolution and Disintegration Properties of Nanoparticles Influencing Biological Action; 4.4 Importance of Developing a Need-Based Selection Criteria; 4.4.1 Nature and Properties of Target Site for Need-Based Selection Criteria; 4.4.2 Types of Nanoconstructs From a Need-Based Selection Criteria; 4.5 Safety Aspects of Theranostic Agents and Toxicity Profiling |
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4.5.1 Safety Aspects of Nanotheranostics From Biological Perspective4.5.2 Safety at Cellular Level; 4.5.3 Safety at Tissue Level; 4.5.4 Toxicity at the Level of Blood; 4.5.5 Safety at Organ Level; 4.5.6 Safety at Body Level; 4.5.7 Safety Aspects of Nanotheranostics From Nanotheranostic Perspective; Structure-dependent toxicities of nanotheranostics; Dose-dependent toxicity; Advancements in toxicity screening; Marketing perspectives and clinical applications; 4.6 Conclusion; Acknowledgment; References; Chapter 5: Nanosystems and antibacterial applications; 5.1 Introduction |
| Summary |
Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. |
| Subject |
Drug delivery systems.
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Nanotechnology.
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Drug Delivery Systems |
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Nanostructures -- therapeutic use |
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Nanotechnology |
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Systèmes d'administration de médicaments.
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Nanotechnologie.
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MEDICAL -- Pharmacology.
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Drug delivery systems
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Nanotechnology
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| Added Author |
Sharma, Chandra Prakash, editor.
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| Other Form: |
Print version: Drug delivery nanosystems for biomedical applications. Amsterdam, Netherlands : Elsevier, [2018] 0323509223 9780323509220 (OCoLC)1007083036 |
| ISBN |
9780323509237 (electronic bk.) |
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0323509231 (electronic bk.) |
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9780323509220 |
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0323509223 |
| Standard No. |
AU@ 000064301746 |
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UKMGB 018831964 |
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