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Title Clopidogrel : pharmacology, clinical uses and adverse effects / [edited by] James P. Alesci, Alexander Victorino.

Publication Info. Hauppauge, New York : Nova Science Publishers, [2013]
©2013

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Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource (265 pages) : illustrations.
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Pharmacology-research, safety testing, and regulation series
Pharmacology-research, safety testing, and regulation series.
Bibliography Includes bibliographical references and index.
Note Online resource; title from PDF title page (ebrary, viewed January 2, 2014).
Contents CLOPIDOGREL: PHARMACOLOGY, CLINICAL USES AND ADVERSE EFFECTS; CLOPIDOGREL: PHARMACOLOGY, CLINICAL USES AND ADVERSE EFFECTS; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE; Chapter 1: CLINICAL REVIEW: PHARMACOLOGY OF TRADITIONAL AND MODERN ANTICOAGULANT AND ANTIPLATELET THERAPY; ABSTRACT; INTRODUCTION; THE COAGULATION PATHWAY; VITAMIN K ANTAGONISTS; XA INHIBITORS; RIVAROXABAN (XARELTO®); APIXABAN (ELIQUIS®); DIRECT THROMBIN INHIBITORS; LEPIRUDIN (REFLUDAN®); BIVALIRUDIN (ANGIOMAX®); DABIGATRAN (PRADAXA®); ADP ANTAGONISTS (THIENOPYRIDINES); TICLOPIDINE (TICLID®)
CLOPIDOGREL (PLAVIX®)PRASUGREL (EFFIENT®); TICAGRELOR (BRILLINTA®); GLYCOPROTEIN IIB/IIIA INHIBITORS; ABCIXIMAB (REOPRO®); EFTIFIBATIDE (INTEGRILIN®); TIROFIBAN (AGGRASTAT®); HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; ENOXAPARIN (LOVENOX, XAPARIN, CLEXANE®); FONDAPARINUX (ARIXTRA®); DISCUSSION; SUMMARY POINTS; REFERENCES; Chapter 2: CLOPIDOGREL IN NEUROINTERVENTIONAL SURGERY: INDICATIONS, COMPLICATIONS, CHALLENGES AND METHODS FOR MONITORING RESPONSE; ABSTRACT; ABBREVIATIONS; INTRODUCTION; INDICATIONS FOR CLOPIDOGREL IN NEUROINTERVENTIONAL SURGERY.
NEUROLOGICALLY-RELEVANT HEMORRHAGIC COMPLICATIONS OF CLOPIDOGRELCOMPLICATIONS OF CLOPIDOGREL IN NEUROINTERVENTIONAL SURGERY; CHALLENGES IN USING CLOPIDOGREL FOR NEUROINTERVENTIONAL SURGERY; METHODS FOR CLOPIDOGREL MONITORING IN NEUROINTERVENTIONAL SURGERY; CONCLUSION; REFERENCES; Chapter 3: CLOPIDOGREL PHARMACOKINETIC: REVIEW OF EARLY STUDIES AND NOVEL EXPERIMENTAL RESULTS; ABSTRACT; 1. INTRODUCTION; 2. PHARMACOKINETICS OF CLOPIDOGREL CARBOXYLIC ACID AND CLOPIDOGREL; 3. CLOPIDOGREL ANALYTICAL CHALLENGES; 4. EXPERIMENTAL DATA ON CLOPIDOGREL ACYL GLUCURONIDE PK.
5. CLOPIDOGREL ACTIVE METABOLITE PK6. EXPERIMENTAL DATA ON OXO-CLOPIDOGREL PK; 7. CONSIDERATIONS ON OTHER POTENTIAL METABOLITES OF CLOPIDOGREL; 8. OVERALL VISION OF CLOPIDOGREL METABOLISM AND PK; 9. POSSIBLE PD IMPACT OF CLOPIDOGREL PK; CONCLUSION; REFERENCES; Chapter 4: FROM MECHANISM TO THERAPEUTICS: OVERCOMING INTER-INDIVIDUAL VARIABILITY IN CLOPIDOGREL THERAPY; ABSTRACT; ABBREVIATION; INTRODUCTION; PHARMACOKINETICS (PK) AND METABOLISM OF CLOPIDOGREL; OVERCOMING INTERINDIVIDUAL VARIABILITY; CONCLUSION; REFERENCES; Chapter 5: MANAGEMENT OF CLOPIDOGREL HYPERSENSITIVITY; ABSTRACT.
INTRODUCTION: CLOPIDOGREL METABOLISM AND INDICATIONSPRESENTATION AND INCIDENCE OF CLOPIDOGREL HYPERSENSITIVITY; DIAGNOSIS AND PATHOPHYSIOLOGY; PHARMACOLOGIC ALTERNATIVES TO CLOPIDOGREL; CLOPIDOGREL DESENSITIZATION; MANAGEMENT OF HYPERSENSITIVITY REACTION WITHOUT CLOPIDOGREL INTERRUPTION; CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 6: CLOPIDOGREL AND GASTROINTESTINAL HARM; ABSTRACT; I. INTRODUCTION; II. CLOPIDOGREL AND GI HARM; III. CLOPIDOGREL AND PROTON PUMP INHIBITOR INTERACTIONS; V. PHARMACOKINETIC AND PHARMACODYNAMIC EVIDENCE FOR A CLOPIDOGREL-PPI INTERACTION; VI. GUIDANCE; CONCLUSION.
Subject Clopidogrel.
Pharmacology.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Clopidogrel. (OCoLC)fst01748888
Pharmacology. (OCoLC)fst01060259
Genre/Form Electronic books.
Added Author Alesci, James P.
Victorino, Alexander.
ISBN 9781629483375 (electronic bk.)
1629483370 (electronic bk.)
9781629483368
Standard No. DEBBG BV042793047
AU@ 000056889089

 
    
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