| Description |
1 online resource |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Neurology--laboratory and clinical research developments |
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Aging issues, health and financial alternatives |
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Neurology--laboratory and clinical research development series.
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Aging issues, health and financial alternatives series.
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| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Contents |
THE ROLE OF OXIDATIVE STRESS, MITOCHONDRIA FAILURE, AND CELLULAR HYPOPERFUSION IN THE CONTEXT OF ALZHEIMER DISEASE ; THE ROLE OF OXIDATIVE STRESS, MITOCHONDRIA FAILURE, AND CELLULAR HYPOPERFUSION IN THE CONTEXT OF ALZHEIMER DISEASE ; Dedication and Acknowledgments ; Contents ; Preface ; Are Mitochondrial Failures a Key Component in Alzheimer Disease? ; Abstract ; Acknowledgments ; References ; In Vivo and In Vitro Assessment of the Brain Mitochondrial Bioenergetics in Aging Rats ; Abstract ; Introduction ; Materials and Methods ; Animals ; Methods. |
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In vivo 31P Magnetic Resonance Spectroscopy In Vitro Mitochondrial Respiration ; In Vitro Mitochondrial Oxidative Phosphorylation (Table 2 and Figure 2) ; Endogenous Antioxidants ; Statistical Methods ; Results ; In Vivo 31P Magnetic Resonance Spectroscopy ; Endogenous Antioxidants (Table 3 and Figure 3) ; Discussion ; Acknowledgments ; References ; The Pathophysiology of Cerebrovascular Lesions in Alzheimer Disease ; Abstract ; The Effect of Oxidative Stress on Brain Microvessel Function in AD ; Neuropathologic Features of Cerebrovascular Lesions. |
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Hypoperfusion as a Factor in the Development of AD Relationships between Apolipoprotein E (ApoE) Genotype, Hypercholesterolemia, and Vascular Changes in AD ; Hypoxia/Ischemia/Reperfusion as Cofactors for Oxidative Stress Induced Cerebrovascular Lesions and their Relationship to AD ; The Role of Mitochondrial Abnormalities in the Patho-Genesis of Oxidative Stress-Induced Brain Lesions in AD ; The Role of Endothelial Vasoactive Substancesin the Pathophysiology of Brain Ischemia/Reperfusion and AD ; Transgenic Animals as Models for Studying Cerebrovascular Lesions in AD. |
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Prevention of AD Using Selective Pharmacological Treatments Conclusion and Considerations for the Future; Acknowledgments ; References ; Vascular Pathology in the Pathogenesis of Alzheimer Disease ; I. Epidemiological Findings ; II. Elements of Brain Tissue Metabolism; III. Causes and Risk Factors ; Inflammatory System ; Vascular Pathology ; 1. Mitochondrial Dysfunction in AD ; 2. Hypoxia and AD ; 3. History of Stroke, Cerebral Ischemia and AD ; 4. Hypertension and Alzheimer Disease ; Acknowledgments ; References. |
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Oxidative Stress Induced Mitochondrial Failure and Cellular Hypoperfusion as Primary Pathogenic Factors for the Development and Progression of Alzheimer Disease Abstract ; Introduction ; Cerebral Vascular Energy Requirements: Hypoperfusion as a Key Factor for the Development of AD ; The Effect of Oxidative Stress on Brain Microvessel Function and AŻ Deposition in AD; Morphometric and Neuropathological Features of CerebroVascular Lesions and AŻ in AD ; Relationships between ApoE Genotype, Hypercholesterolemia, AŻ and Vascular Changes in AD. |
| Subject |
Alzheimer's disease.
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Oxidative stress.
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Mitochondrial pathology.
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Cell respiration.
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Alzheimer Disease |
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Oxidative Stress |
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Maladie d'Alzheimer.
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Stress oxydatif.
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Maladies mitochondriales.
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Cellules -- Respiration.
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HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
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MEDICAL -- Neurology.
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Alzheimer's disease. (OCoLC)fst00806532
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Cell respiration. (OCoLC)fst00850233
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Mitochondrial pathology. (OCoLC)fst01024022
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Oxidative stress. (OCoLC)fst01049566
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| Other Form: |
Print version: Role of oxidative stress, mitochondria failure, and cellular hypoperfusion in the context of Alzheimer disease. New York : Nova Science Publishers, Inc, 2013 9781619428782 (DLC) 2011946292 |
| ISBN |
9781619428973 (ebook) |
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1619428970 |
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1619428784 (hardcover) |
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9781619428782 (hardcover) |
| Standard No. |
AU@ 000062325323 |
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NZ1 15023166 |
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