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Author Andronescu, Ecaterina.

Title Nanostructures for Drug Delivery.

Publication Info. Saint Louis : Elsevier Science, 2017.
©2017

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Location Call No. OPAC Message Status
 Axe Elsevier ScienceDirect Ebook  Electronic Book    ---  Available
Description 1 online resource (1026 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Micro and Nano Technologies
Micro & nano technologies.
Note Print version record.
Contents Cover; Title page; Copyright page; Contents; List of Contributors; Foreword of the Series; Preface; About the Series (Volumes I-V); About Volume II; Chapter 1 -- Therapeutic nanomaterials: from a drug delivery perspective; 1 -- Introduction; 2 -- General Methods of Synthesis of Nanomaterials; 2.1 -- Physical Methods; 2.2 -- Chemical Methods; 2.3 -- Biological Methods; 3 -- Characterization of Nanomaterials; 4 -- Applications of Nanomaterials for Drug Delivery; 4.1 -- Polymeric Nanomaterials; 4.2 -- Polymeric Micelles; 4.3 -- Dendrimers; 4.4 -- Polysaccharide-Based Nanomaterials; 4.5 -- Nanoparticles.
4.5.1 -- Gold nanoparticles4.5.2 -- Silver nanoparticles; 4.5.3 -- Iron nanoparticles; 4.5.4 -- Silica nanoparticles; 4.6 -- Carbon Nanotubes; 4.7 -- Quantum Dots; 5 -- Conclusions; References; Chapter 2 -- Core-shell drug carriers: liposomes, polymersomes, and niosomes; 1 -- Introduction; 2 -- Self-Assembled Bilayers; 3 -- Liposomes as Drug Carriers; 4 -- Polymersomes as Drug Carriers; 5 -- Niosomes as Drug Carriers; 6 -- Biomedical Applications of Core-Shell Vesicular Drug Carriers; 7 -- Discussion; 8 -- Conclusions; Conflict of Interests; References.
Chapter 3 -- The new nanocarriers based on graphene and graphene oxide for drug delivery applications1 -- Introduction; 2 -- Chemistry of the Graphene Surface; 3 -- Modification of Graphene Surface for Drug Delivery Applications; 3.1 -- Graphene Modification by PEG; 3.2 -- Modification With Folic Acid; 3.3 -- Modification by Chitosan; 3.4 -- Modification by Gelatin; 3.5 -- Modification by PEI; 3.6 -- Modification by Dextran; 3.7 -- Modification by Poly(N-Isopropylacrylamide); 3.8 -- Modification by Poly(allylamine); 3.9 -- Photothermal Anticancer Activity of Graphene.
3.10 -- Modification by Poly N-Vinyl Caprolactam3.11 -- Modification by Poly N-Isopropyl Acrylamide-Polyethylene Glycol Copolymer; 3.12 -- Using Graphene for Glioma Treatment; 4 -- In Vitro Toxicology and Biosafety of Graphene Derivative; 5 -- Conclusions; References; Chapter 4 -- Nanostructured nanoparticles for improved drug delivery; Abbreviations; 1 -- Introduction; 2 -- The Core-Shell Nanostructure; 2.1 -- Core-Shell: A Common Nanostructure in Drug Delivery Nanocarriers; 2.2 -- Inventory of Structures and Selected Examples; 2.2.1 -- Polymer brushes as nanoparticle shell: the PEG paradigm.
2.2.2 -- Other alternatives to PEG2.2.3 -- Phospholipids and lipids conjugates; 2.2.3.1 -- The phospholipid monolayer shell; 2.2.3.2 -- The phospholipid bilayers shell; 2.2.3.3 -- Cell membrane mimetic shells; 2.2.4 -- Hydrogel shells; 2.2.4.1 -- Diffusion-controlled release from hydrogel shells; 2.2.4.2 -- Stimuli-responsive hydrogel shells; 2.2.5 -- Layer-by-layer shell; 2.2.6 -- Hydrophobic shells; 2.2.7 -- Inorganic shells; 3 -- The Capsule and Vesicle Nanostructure; 3.1 -- Nanocapsules; 3.1.1 -- Encapsulation of lipophilic or hydrophilic compounds as a function of core type.
3.1.2 -- Permeability control as a function of wall structure.
Bibliography Includes bibliographical references and index.
Summary Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial.
Subject Nanomedicine.
Nanoparticles.
Drug delivery systems.
Nanotechnology.
Nanomedicine
Nanoparticles
Drug Delivery Systems
Nanotechnology
Nanoparticules.
Systèmes d'administration de médicaments.
Nanomédecine.
Nanotechnologie.
MEDICAL -- Pharmacology.
Nanotechnology
Drug delivery systems
Nanomedicine
Nanoparticles
Added Author Grumezescu, Alexandru Mihai.
Other Form: Print version: Andronescu, Ecaterina. Nanostructures for Drug Delivery. Saint Louis : Elsevier Science, ©2017 9780323461436
ISBN 9780323461498
0323461492
0323461433
9780323461436
Standard No. AU@ 000061153629
AU@ 000065313286
CHBIS 011069690
GBVCP 100485773X

 
    
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