| Edition |
Second edition |
| Description |
1 online resource illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Note |
Online resource; title from PDF title page (ProQuest Ebook Central, viewed on September 30, 2020) |
| Bibliography |
Includes bibliographical references |
| Contents |
Front Cover -- Breathborne Biomarkers and the Human Volatilome -- Breathborne Biomarkers and the Human VolatilomeSecond EditionEdited by Jonathan BeauchampCristina DavisJoachim Pleil? -- Copyright -- Introducing people to innovations, step by step-the legacy of Anton Amann -- Contents -- Contributors -- Foreword -- Preface -- A -- Concepts and modeling -- 1 -- Breath biomarkers and the exposome -- 1.1 Overview -- 1.2 The human volatilome and breath analysis -- 1.3 Breathborne biomarkers -- 1.3.1 Capnography -- 1.3.2 Exhaled nitric oxide in asthma -- 1.3.3 Ethanol breath test for law enforcement |
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1.3.4 Hydrogen breath test for lactase deficiency -- 1.3.5 Carbon monoxide in neonatal jaundice -- 1.3.6 Urea breath test for Helicobacter pylori infection -- 1.3.7 Gastric emptying breath test for gastroparesis -- 1.3.8 Maximum liver function capacity breath test -- 1.3.9 Heart transplant rejection breath test -- 1.4 Targeted versus untargeted breath analysis -- 1.5 The human exposome -- 1.5.1 A brief history of human exposome research -- 1.5.2 Defining the human exposome concept -- 1.5.3 The exhaled breath exposome -- 1.6 Data treatment tools -- 1.6.1 Summary statistics |
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1.6.2 Data visualization -- 1.7 Summary -- Acknowledgments -- References -- 2 -- Breath sampling and standardization -- 2.1 Overview -- 2.2 Sampling -- 2.2.1 Exhalation phases -- 2.2.2 Controlled sampling -- 2.2.3 Analytical platforms -- 2.2.4 Sampling for offline analysis -- Bags -- Sorbent traps -- Regular sorbent extraction -- Microextraction -- 2.2.5 Sampling for online analysis -- 2.2.6 Influence of physiological parameters -- 2.2.7 Extraneous confounders -- 2.3 Standardization -- 2.4 Summary -- References -- 3 -- Physiological modeling of exhaled compounds -- 3.1 Overview |
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3.2 Experimental basis from real-time analyses -- 3.3 Modeling theory -- 3.4 Isoprene -- 3.4.1 Experiments to examine endogenous isoprene -- 3.4.2 A physiological model for breath isoprene dynamics -- 3.4.3 Practical implications of isoprene model -- 3.4.4 Extending the isoprene model with two compartments -- 3.5 Acetone -- 3.5.1 Experiments to examine endogenous acetone -- 3.5.2 A physiological model for breath acetone dynamics -- 3.5.3 Practical implications of acetone model -- 3.6 Carbon monoxide -- 3.7 Methane -- 3.8 Sevoflurane -- 3.9 Summary -- Acknowledgments -- References |
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4 -- Exhaled nitric oxide physiology and modeling -- 4.1 Overview -- 4.2 Two-compartment model -- 4.3 Different mathematical methods to calculate nitric oxide parameters -- 4.3.1 Linear method -- 4.3.2 Nonlinear model -- 4.4 Mechanisms altering central and peripheral pulmonary nitric oxide parameters -- 4.5 Nitric oxide parameters in airway diseases -- 4.5.1 Asthma -- 4.5.2 Chronic obstructive pulmonary disease -- 4.5.3 Parenchymal lung diseases -- 4.6 Nitric oxide parameters in systemic diseases -- 4.7 Current clinical use and further research on nitric oxide parameters -- 4.8 Summary |
| Summary |
Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis |
| Subject |
Biochemical markers.
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Volatile organic compounds.
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Biomarkers |
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Marqueurs biologiques.
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Composés organiques volatils.
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volatile organic compounds.
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Volatile organic compounds
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Biochemical markers
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| Added Author |
Davis, Cristina editor
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Beauchamp, Jonathan editor
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Pleil, Joachim editor
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| Other Form: |
Print version: Davis, Cristina. Breathborne Biomarkers and the Human Volatilome. San Diego : Elsevier, ©2020 |
| ISBN |
9780128223970 electronic bk. |
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0128223979 electronic bk. |
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9780128199671 |
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0128199679 |
| Standard No. |
AU@ 000068032507 |
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AU@ 000068659194 |
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