Description |
1 online resource : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
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data file |
Bibliography |
Includes bibliographical references and index. |
Note |
Print version record. |
Contents |
Cover; Title; Copyright; Contents; Contributors; Foreword; Preface; Part I. Basics for Clinicians; 1. History of Multiple Sclerosis; Early Cases of MS; Early Descriptions of MS; Description by Charcot; Early Monographs; Early Reports; Three Landmark Reviews of MS; Theories About Causation; Search for an Infection; Epidemiology; Genetics of MS; Vascular Theory; The Immunological Theory; MS Plaque; Investigations; Cognitive Changes in MS; Therapy; Multiple Sclerosis Societies; References; 2. Overview of Multiple Sclerosis; New Directions in Understanding MS; New Directions in Diagnosing MS. |
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New Directions in Monitoring MSNew Directions in Treatment of MS Disease Activity; New Directions in Treatment of MS Symptoms; Greater Recognition of The Importance of Other Health Measures in MS; Embracing a Team Approach To MS; Ongoing Challenges and Future Promise; Bibliography; 3. Pathology and Pathophysiology of Multiple Sclerosis; Demyelination within GM and WM in MS; Inflammation in MS; WM Inflammation in MS; GM Inflammation in MS; Neuronal and Axonal degeneration in MS; Pathophysiology of Neurodegeneration in MS; Summary; References. |
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4. Epidemiology and Natural History of Multiple SclerosisEpidemiology, Survival, Incidence, and Prevalence of Multiple Sclerosis; Environmental Risk Factors for MS; The Natural History of MS; Environmental Risk Factors and The Natural History of MS; Benign MS; References; 5. Multiple Sclerosis Genetics; Race and Geography; Familial Aggregation; The First Molecular Markers for MS: Human Leukocyte Antigens; Linkage Analysis; MS as A Complex Trait; Genomic Linkage Screens; Missing Heritability; Vitamin D Genetics; Exome and Genome Sequencing; The MHC and MS Susceptibility. |
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Current Directions and LimitationsReferences; Part II. Diagnosis; 6. Symptoms and Signs of Multiple Sclerosis; Illustrative Case; Introduction; Evaluation of Symptoms; Symptom Review by System; Nonspecific Versus Specific Symptoms; Conclusion-Finding Patterns Which Fit Together; References; 7. Diagnosis of Multiple Sclerosis; Diagnostic Criteria: A Very Short History; Diagnosing MS: The Mcdonald Criteria (2010); Defining The Phenomenology of MS; Putting The Mcdonald Criteria (2010) Into Practice; Diagnosing MS by Combined Clinical and MRI Criteria. |
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The Utility of Cerebrospinal Fluid Examination in the Diagnosis of MS: Why Do a Lumbar Puncture?Diagnostic Categories Resulting from Applying the Mcdonald Criteria; Limitations of the Mcdonald (2010) Criteria; Future Directions in the Diagnosis of MS; References; 8. Magnetic Resonance Imaging in Multiple Sclerosis; Relevant MRI Physics; Characterization of MS on Conventional MRI; Technical Considerations and Pitfalls; Clinical Applications in Disease Monitoring; MRI Safety; References; 9. Tools and Tests for Multiple Sclerosis; Blood Tests; Lumbar Puncture/Spinal Fluid Analysis. |
Summary |
Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the ""fac |
Language |
English. |
Subject |
Multiple sclerosis -- Diagnosis.
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Multiple sclerosis -- Treatment.
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Multiple Sclerosis -- diagnosis |
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Multiple Sclerosis -- therapy |
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Sclérose en plaques -- Traitement.
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HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
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MEDICAL -- Neurology.
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Multiple sclerosis -- Diagnosis
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Multiple sclerosis -- Treatment
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Added Author |
Rae-Grant, Alexander, editor.
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Fox, Robert, 1969- editor.
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Béthoux, François, editor.
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Other Form: |
Print version: Multiple sclerosis and related disorders. New York, NY : Demos Medical, ©2013 9781936287758 (DLC) 2013002906 (OCoLC)826287969 |
ISBN |
9781617051272 (electronic bk.) |
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1617051276 (electronic bk.) |
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9781936287758 |
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1936287757 |
Standard No. |
DEBBG BV043061098 |
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DEBBG BV044177186 |
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DEBSZ 424595958 |
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GBVCP 804786992 |
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NZ1 15181085 |
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NZ1 15702799 |
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