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Title Multiple sclerosis and related disorders : clinical guide to diagnosis, medical management, and rehabilitation / editors, Alexander D. Rae-Grant, Robert J. Fox, Francois Bethoux.

Imprint New York, NY : Demos Medical, ©2013.

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Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource : illustrations
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
data file
Bibliography Includes bibliographical references and index.
Note Print version record.
Contents Cover; Title; Copyright; Contents; Contributors; Foreword; Preface; Part I. Basics for Clinicians; 1. History of Multiple Sclerosis; Early Cases of MS; Early Descriptions of MS; Description by Charcot; Early Monographs; Early Reports; Three Landmark Reviews of MS; Theories About Causation; Search for an Infection; Epidemiology; Genetics of MS; Vascular Theory; The Immunological Theory; MS Plaque; Investigations; Cognitive Changes in MS; Therapy; Multiple Sclerosis Societies; References; 2. Overview of Multiple Sclerosis; New Directions in Understanding MS; New Directions in Diagnosing MS.
New Directions in Monitoring MSNew Directions in Treatment of MS Disease Activity; New Directions in Treatment of MS Symptoms; Greater Recognition of The Importance of Other Health Measures in MS; Embracing a Team Approach To MS; Ongoing Challenges and Future Promise; Bibliography; 3. Pathology and Pathophysiology of Multiple Sclerosis; Demyelination within GM and WM in MS; Inflammation in MS; WM Inflammation in MS; GM Inflammation in MS; Neuronal and Axonal degeneration in MS; Pathophysiology of Neurodegeneration in MS; Summary; References.
4. Epidemiology and Natural History of Multiple SclerosisEpidemiology, Survival, Incidence, and Prevalence of Multiple Sclerosis; Environmental Risk Factors for MS; The Natural History of MS; Environmental Risk Factors and The Natural History of MS; Benign MS; References; 5. Multiple Sclerosis Genetics; Race and Geography; Familial Aggregation; The First Molecular Markers for MS: Human Leukocyte Antigens; Linkage Analysis; MS as A Complex Trait; Genomic Linkage Screens; Missing Heritability; Vitamin D Genetics; Exome and Genome Sequencing; The MHC and MS Susceptibility.
Current Directions and LimitationsReferences; Part II. Diagnosis; 6. Symptoms and Signs of Multiple Sclerosis; Illustrative Case; Introduction; Evaluation of Symptoms; Symptom Review by System; Nonspecific Versus Specific Symptoms; Conclusion-Finding Patterns Which Fit Together; References; 7. Diagnosis of Multiple Sclerosis; Diagnostic Criteria: A Very Short History; Diagnosing MS: The Mcdonald Criteria (2010); Defining The Phenomenology of MS; Putting The Mcdonald Criteria (2010) Into Practice; Diagnosing MS by Combined Clinical and MRI Criteria.
The Utility of Cerebrospinal Fluid Examination in the Diagnosis of MS: Why Do a Lumbar Puncture?Diagnostic Categories Resulting from Applying the Mcdonald Criteria; Limitations of the Mcdonald (2010) Criteria; Future Directions in the Diagnosis of MS; References; 8. Magnetic Resonance Imaging in Multiple Sclerosis; Relevant MRI Physics; Characterization of MS on Conventional MRI; Technical Considerations and Pitfalls; Clinical Applications in Disease Monitoring; MRI Safety; References; 9. Tools and Tests for Multiple Sclerosis; Blood Tests; Lumbar Puncture/Spinal Fluid Analysis.
Summary Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the ""fac
Language English.
Subject Multiple sclerosis -- Diagnosis.
Multiple sclerosis -- Treatment.
Multiple Sclerosis -- diagnosis
Multiple Sclerosis -- therapy
Sclérose en plaques -- Traitement.
HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
MEDICAL -- Neurology.
Multiple sclerosis -- Diagnosis
Multiple sclerosis -- Treatment
Added Author Rae-Grant, Alexander, editor.
Fox, Robert, 1969- editor.
Béthoux, François, editor.
Other Form: Print version: Multiple sclerosis and related disorders. New York, NY : Demos Medical, ©2013 9781936287758 (DLC) 2013002906 (OCoLC)826287969
ISBN 9781617051272 (electronic bk.)
1617051276 (electronic bk.)
9781936287758
1936287757
Standard No. DEBBG BV043061098
DEBBG BV044177186
DEBSZ 424595958
GBVCP 804786992
NZ1 15181085
NZ1 15702799

 
    
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