| Description |
xiii, 377 p., [8] p. of plates : ill. (some col.) |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach. |
| Reproduction |
Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. |
| Subject |
Genetic toxicology.
|
|
Toxicity testing.
|
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Health risk assessment.
|
| Genre/Form |
Electronic books.
|
| Added Author |
Boverhof, Darrell R.
|
|
Gollapudi, B. Bhaskar.
|
|
ProQuest (Firm)
|
| ISBN |
9780470449820 (cloth) |
|
9781118001042 (oBook) |
|
9781118001035 (electronic bk.) |
|
9781118008980 (electronic bk.) |
|
9781118001035 (electronic bk.) |
|
