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Title Applications of toxicogenomics in safety evaluation and risk assessment [electronic resource] / edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.

Imprint Hoboken, N.J. : John Wiley & Sons, c2011.

Copies

Location Call No. OPAC Message Status
 Axe ProQuest E-Book  Electronic Book    ---  Available
Description xiii, 377 p., [8] p. of plates : ill. (some col.)
Bibliography Includes bibliographical references and index.
Contents Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.
Reproduction Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
Subject Genetic toxicology.
Toxicity testing.
Health risk assessment.
Genre/Form Electronic books.
Added Author Boverhof, Darrell R.
Gollapudi, B. Bhaskar.
ProQuest (Firm)
ISBN 9780470449820 (cloth)
9781118001042 (oBook)
9781118001035 (electronic bk.)
9781118008980 (electronic bk.)
9781118001035 (electronic bk.)

 
    
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