| Description |
1 online resource (xi, 326 pages) : illustrations, charts |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Summary |
This volume presents an overview of recent developments in systems biology and their applications in cancer-related research. The ongoing advances in our understanding of genomics and proteomics, coupled with the development of new and more robust tools, have led to an emphasis on analyzing biological systems at multiple levels. Thus, there is a need to integrate different types of data into a comprehensive "systems" view. Written by active researchers in the emerging areas, this book gives senior undergraduate students, graduate students and new researchers an idea of where the frontiers of s. |
| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Contents |
pt. I. Gene/protein networks and pathways. 1. Introduction to systems biology / Hsueh-Fen Juan. 2. Gene network construction for molecular regulation / Hsueh-Fen Juan and Hsuan-Cheng Huang. 3. MicroRNA regulation in cellular networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 4. Disease modules in protein-protein interaction networks / Hsueh-Fen Juan and Hsuan-Cheng Huang. 5. Biomolecular pathway modeling / Feng-Sheng Wang and Wu-Hsiung Wu -- pt. II. High-throughput omics data and analysis. 6. ChIP-seq analytics: methods and systems to improve ChIP-seq peak identification / Stuart Brown [and others]. 7. Discovery of transcription factor binding sites and its applications in cancer study / Chien-Yu Chen. 8. Cancer epigenomics / Jer-Wei Chang and Yi-Ching Wang. 9. Cancer phosphoproteomics: tools and emerging applications for mining the phosphoproteome in cancer biology / Hsin-Yi Wu [and others]. 10. Predicting microRNAs / Arthur Chun-Chieh Shih and Tsunglin Liu. 11. MicroRNA research in cancer biology: databases and tools / Hsien-Da Huang -- pt. III. Applications for biomarkers and drug discovery. 12. The application of the next-generation sequencing technologies in cancer research / Lihua Cheng, Hong Xu and Biaoyang Lin. 13. Membrane proteomics for the opportunity of cancer biomarker and drug target discovery / Chia-Li Han [and others]. 14. Structure-based systems biology and drug design in cancer research / Chun-Hua Hsu. 15. Discovering drug targets for cancer therapy / Tsui-Chin Huang, Hsin-Yi Chang and Hsueh-Fen Juan. |
| Language |
English. |
| Subject |
Cancer -- Research -- Methodology.
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Systems biology.
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Neoplasms |
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Systems Biology -- methods |
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Systems Biology |
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Cancer -- Recherche -- Méthodologie.
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Biologie systémique.
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HEALTH & FITNESS -- Diseases -- Cancer.
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HEALTH & FITNESS -- Health Care Issues.
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MEDICAL -- Diseases.
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MEDICAL -- Health Care Delivery.
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MEDICAL -- Health Policy.
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MEDICAL -- Public Health.
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SOCIAL SCIENCE -- Disease & Health Issues.
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Systems biology
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| Added Author |
Juan, Hsueh-Fen.
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Huang, Hsuan-Cheng.
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| Other Form: |
Print version: Systems biology. Singapore : World Scientific, ©2012 9789814324458 (OCoLC)644646511 |
| ISBN |
9789814324465 (electronic bk.) |
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9814324469 (electronic bk.) |
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9789814324458 |
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9814324450 |
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1280669284 |
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9781280669286 |
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9786613646217 |
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6613646210 |
| Standard No. |
AU@ 000051590696 |
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AU@ 000051829655 |
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AU@ 000052404510 |
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DEBBG BV043081524 |
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DEBBG BV044165380 |
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DEBSZ 372596290 |
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DEBSZ 421411767 |
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NZ1 14693475 |
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NZ1 15586418 |
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AU@ 000073139080 |
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