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Author Lacher, David A., author.

Title Biological variation of hematology tests based on the 1999-2002 National Health and Nutrition Examination Survey / by David A. Lacher, Janet Barletta, and Jeffery P. Hughes.

Publication Info. Hyattsville, MD : U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2012.


Location Call No. OPAC Message Status
 Axe Federal Documents Online  HE 20.6209/3-2:54    ---  Available
Description 1 online resource (11 pages) : color illustrations.
text rdacontent
computer rdamedia
online resource rdacarrier
Series National health statistics reports ; no. 54
DHHS publication ; no. (PHS) 2012-1250
National health statistics reports ; no. 54.
DHHS publication ; no. (PHS) 2012-1250.
Note "July 12, 2012."
Title from title screen (viewed on Oct. 22, 2014).
Bibliography Includes bibliographical references (pages 6-7).
Access Use copy Restrictions unspecified star MiAaHDL
Summary Objective--Biological variation consists of between-person (BP) and within-person (WP) variation. Estimates of WP coefficients of variation (CVw) and BP coefficients of variation (CVg) for hematology laboratory tests were estimated from the 1999-2002 National Health and Nutrition Examination Survey (NHANES). Methods--NHANES is a survey of the civilian noninstitutionalized U.S. population that uses a stratified, multistage probability design. Between- and within-person variations were estimated for 18 hematology tests. For WP variation, a nonrandom sample was obtained with a median of 17 days between two test measurements. Between-person variation was estimated from the WP sample and additional participants were matched for age group, gender, and race and ethnicity to the WP sample. Results--The BP and WP variations were estimated on as many as 2,496 and 852 sample participants, respectively. Mean corpuscular hemoglobin concentration had the lowest CVg (2.25% for men and 2.40% for women), and mean corpuscular volume had the lowest CVw (0.31% for men and 0.37% for women). The index of individuality (CVw /CVg) ranged from 0.06 for mean corpuscular volume for men and women to 0.62 for segmented neutrophil number for men, and 0.55 for segmented neutrophil percent for women. Women had higher CVw compared with men for hematocrit, hemoglobin, mean corpuscular volume, red blood cell count, and red blood cell distribution width. Several hematology tests' CVw also differed by age group, including mean corpuscular volume; eosinophil, lymphocyte and segmented neutrophil percent; monocyte and segmented neutrophil number; white blood cell count; and red blood cell distribution width.
Reproduction Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2011. MiAaHDL
System Details Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Processing Action digitized 2011 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject National Health and Nutrition Examination Survey (U.S.)
National Health and Nutrition Examination Survey (U.S.) (OCoLC)fst00626984
Blood -- Analysis -- Statistics.
Blood -- Analysis. (OCoLC)fst00834552
Bias (Epidemiology)
Clinical Laboratory Techniques -- standards.
Hematology -- standards.
Nutrition Surveys.
United States.
Genre/Form Statistics. (OCoLC)fst01423727
Added Author Barletta, Janet, author.
Hughes, Jeffery P., author.
National Center for Health Statistics (U.S.), issuing body.
Other Form: Paper version: Lacher, David A. Biological variation of hematology tests based on the 1999-2002 National Health and Nutrition Examination Survey (OCoLC)851079469
Gpo Item No. 0500-E-18 (online)
Sudoc No. HE 20.6209/3-2:54

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