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Author Chen, Xiaolong, author.

Title Validamycin and its derivatives : discovery, chemical synthesis, and biological activity / Xiaolong Chen, Yuele Lu, Yongxian Fan and Yinchu Shen, Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, PR China.

Publication Info. Amsterdam, Netherlands ; Oxford, United Kingdom : Elsevier, 2017.


Location Call No. OPAC Message Status
 Axe Elsevier ScienceDirect Ebook  Electronic Book    ---  Available
Description 1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Bibliography Includes bibliographical references and index.
Summary Validamycin and its derivatives: discovery, chemical synthesis and biological activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. Offers complete coverage of validamycin chemistry from a highly experienced team of authors.
Note Vendor-supplied metadata.
Subject Antibiotics.
Fungicides, Industrial
MEDICAL -- Pharmacology.
Antibiotics. (OCoLC)fst00810420
Biosynthesis. (OCoLC)fst00832721
Fungicides. (OCoLC)fst00936358
Added Author Lu, Yuele, author.
Fan, Yongxian, author.
Shen, Yinchu, author.
Other Form: Print version: 0081009992 9780081009994 (OCoLC)960902000
ISBN 9780081011133 (electronic bk.)
008101113X (electronic bk.)
Standard No. 40027162997
AU@ 000061156263
AU@ 000066135543
CHBIS 011069416
CHVBK 499792602
AU@ 000068474155

Available items only