| Description |
1 online resource (xiv, 298 pages) : illustrations. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Woodhead Publishing in materials |
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Woodhead Publishing in materials.
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| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Summary |
The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people's lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs. Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine. With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organsDiscusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacementsFurther biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored. |
| Contents |
Cover; Biomaterials for artificial organs; Copyright; Contents; Contributor contact details; Dedication; Part I Commodity biomaterials; 1Membranes for oxygenators and plasma filters; 1.1 Introduction; 1.2 Membranes for blood oxygenation; 1.3 Membranes for plasma separation; 1.4 Economic considerations; 1.5 Future trends; 1.6 Abbreviations; 1.7 References; 2 Titanium and cobalt-chromium alloys for hips and knees; 2.1 Hip and knee joint replacement; 2.2 Challenges for currentmetal hip and knee implants. |
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2.3 Material fundamentals of titanium and cobalt- chromium alloys used in hip and knee replacement2.4 Advances in titaniumand cobalt-chromiumalloys used for joint implant; 2.5 Conclusions and future trends; 2.6 References; 3Polymeric joint bearing surfaces for total joint replacements; 3.1 Introduction; 3.2 Early development of joint bearing couples; 3.3 Ultrahigh molecularweight polyethylene (UHMWPE); 3.4 The introduction of high dose crosslinking; 3.5 Failures inmaterial development; 3.6 Joint-specific challenges and alternatives; 3.7 Future trends; 3.8 References. |
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4 Biomaterials for pacemakers, defibrillators and neurostimulators4.1 Introduction; 4.2 Pacemakers; 4.3 Defibrillators; 4.4 Neurostimulators; 4.5 Engineering approaches to solve material problems; 4.6 Reliability and testing; 4.7 Future electrical stimulation devices; 4.8 Acknowledgements; 4.9 Sources of further information and advice; 4.10 References; 5Mechanical and bioprosthetic heart valves; 5.1 Introduction; 5.2 Mechanical valves; 5.3 Tissue valves; 5.4 Design considerations; 5.5 Material considerations; 5.6 Process considerations; 5.7 Additional considerations; 5.8 Emerging technology. |
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5.9 Applicable standards5.10 Conclusions and future trends; 5.11 Sources of further information and advice; 5.12 Dedication; 5.13 References; Part II Advanced and generation biomaterials; 6Small intestinal submucosa and other decellularized matrix biomaterials for tissue repair; 6.1 Introduction; 6.2 In situ tissue engineering; 6.3 Harvest from nature or build from scratch; 6.4 The extreme importance of processing; 6.5 Clinical lessons learned; 6.6 References; 7New ceramics and composites for joint replacement surgery; 7.1 Introduction; 7.2 Ceramics for bearing applications. |
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7.3 Limitations of ceramics for bearing applications7.4 Development of ceramics for bearing applications; 7.5 Future developments in ceramic bearing materials; 7.6 Future trends; 7.7 References; 8 Biomaterials for improving the blood and tissuecompatibility of total artificial hearts (TAH) andventricular assist devices (VAD); 8.1 Introduction; 8.2 Historical background of cardiac assist devices; 8.3 Characterization of biomaterials: interaction with blood and tissue surface; 8.4 Biomaterials of current cardiac devices. |
| Subject |
Biomedical materials.
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Artificial organs.
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Tissue engineering.
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Biocompatible Materials |
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Tissue Engineering |
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Artificial Organs |
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Prostheses and Implants |
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Biomatériaux.
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Organes artificiels.
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Génie tissulaire.
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MEDICAL -- Surgery -- General.
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Tissue engineering
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Artificial organs
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Biomedical materials
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| Added Author |
Lysaght, Michael.
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Webster, Thomas J.
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| Other Form: |
Print version: Biomaterials for artificial organs. Cambridge, UK ; Philadelphia : Woodhead Pub., 2011 9781845696535 1845696530 |
| ISBN |
0857090844 (electronic bk.) |
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9780857090843 (electronic bk.) |
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9781845696535 |
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1845696530 |
| Standard No. |
DEBBG BV042316730 |
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DEBSZ 414265688 |
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NZ1 15582261 |
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AU@ 000056856976 |
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