| Description |
1 online resource (xi, 304 pages) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Bibliography |
Includes bibliographical references and index. |
| Summary |
"Over the past 5 to 10 years, organ preservation techniques using chemoradiotherapy have gained considerable popularity as first-line treatment of head and neck cancer, especially for oropharyngeal, laryngeal, and hypopharyngeal cancer. This trend is now increasing with more intensified chemoradiotherapy treatment modalities and regimens. This means that more and more advanced disease is likely to be treated with chemoradiotherapy as a primary treatment, with increased likelihood of failure of these treatments (almost half of the patients relapse, but the organ-preserving aspect of chemoradiotherapy makes it in many cases so very worthwhile as a primary treatment). As chemoradiotherapy is a relatively new management philosophy, experience of salvaging patients with recurrences is therefore still relatively limited and expertise of it is not yet highly developed, although it is an area of great interest for the wider specialties involved. This book is specifically compiled to provide evidence-based, multidisciplinary management strategies for this complex and difficult to manage disease, combined with an account of the relevant techniques, results, and possible complications that might arise and how to deal with them. The book is intended for practicing specialists in head and neck cancer both surgery and oncology. It is aimed at the consultant level as well as at senior trainees interested in the field. Special features: Evidence-based, comprehensive review of the topic, which is very difficult to deal with in clinical practice and poorly covered in the literature International, multidisciplinary authorship including the top clinicians in their fields; most chapters have a surgeon and an oncologist involved, which offers top expertise and a balanced, multidisciplinary view General chapters on principles of relevant surgical p techniques and radiotherapy; site-specific chapters dealing with specific management of recurrence at each head and neck site Pactical tips and pitfalls sections the practical details will allow readers to improve patient management and outcomes Illustrative cases including history, clinical findings, imaging, treatment (incl. Plplanning and results) brings decision-making process to life and easier to relate to clinical practice Summaries, recommended further reading and further research sections highlight important aspects, offer a valuable reference facility, and point out specific needs for further systematic studiesTarget groups: head and neck surgeons (with a background in otolaryngology, maxillofacial surgery, or plastic surgery), head and neck radiation and medical oncologists"--Provided by publisher |
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"The only book dedicated to provide evidence-based management strategies for this complex and difficult to manage recurrant disease, complied by an international, multidisciplinary group of the world's top experts in the field of head and neck cancer"--Provided by publisher |
| Note |
Print version record. |
| Contents |
Head and Neck Cancer Recurrence: Evidence-based, Multidisciplinary Management; Title Page; Copyright; Contributors; Preface; Acknowledgments; Contents; 1 Introduction; Clinical Assessment and Imaging Evaluation of Recurrence; Principles of the Assessment of Potential Recurrence; History and Examination; Previous Treatment Records; Imaging; Examination under Anesthetic; Needle or Open Biopsy; 2 Molecular Biology of Recurrence; Introduction; The Biology of Treatment Resistance; Activation of Alternative Signaling Pathways; Biological Processes Involved in Metastasis; Conclusions. |
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3 Imaging Modalities for Head and Neck Cancer RecurrenceTherapy-related Changes in the Head and Neck Region; Imaging Modalities for Detection of Recurrence; Imaging for Recurrence at Specific Sites; 4 Concurrent Chemotherapy and Re-irradiation for Recurrent Head and Neck Cancer; Introduction; Reasons for Tumor Recurrence Following Definitive Therapy; Regimens for Concurrent Chemotherapy with Re-irradiation; Evidence for Concurrent Chemotherapy with Re-irradiation; Brachytherapy for Recurrent Head and Neck Cancer; Patient Selection and Prognostic Factors. |
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Simulation and Planning for Re-irradiationTreatment Volume Definition; Beam Arrangement; Advances in Delivery of Radiation; New Approaches to CRRT; Conclusion; 5 Systemic Therapy in the Treatment of Recurrent and Metastatic Head and Neck Carcinoma; Patient's Clinical Profile and Assessment; Clinical Decision Making; Medical Treatment; Special Issues in End-of-Life Supportive Care; 6 Principles and Concepts of Reconstruction in the Recurrent Setting; Introduction; Issues in Surgical Approach-Impact of Previous Treatment; Management of the Vessel-depleted Neck. |
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Site-specific Defect ConsiderationsConclusion; 7 Patient Selection for Treatment; Introduction; Assessment of the Recurrent Cancer; Factors Involved in Treatment Selection; Involving the Patient in the Decision-making Process; Treatment Options; 8 Recurrent Laryngeal Cancer; Introduction; Epidemiology; Diagnosis of Recurrent Laryngeal Cancer; Staging of Recurrent Laryngeal Cancer; Principles of Management; Surgical Management of Recurrent Disease; 9 Management of Recurrent Hypopharyngeal Cancer; Incidence and Patterns of Recurrence in Hypopharyngeal Cancer; Detection of Recurrent Disease. |
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Principles of ManagementSurgical Techniques of Salvage Pharyngolaryngectomy; Re-irradiation for Recurrent Hypopharyngeal Cancer; 10 Carcinoma of the Oral Cavity; Introduction; Posttreatment Surveillance; Diagnosis of Recurrence; Principles of Management; Surgical Approaches and Techniques; Outcomes; 11 Carcinoma of the Oropharynx; Epidemiology; Prognostic Factors; Investigations; Principles of Management; Outcomes; 12 Management of Nodal Recurrence; Introduction; Incidence and Distribution of Nodal Recurrence; Evaluation of Nodal Recurrence; Management; Special Considerations; Outcomes. |
| Subject |
Head -- Cancer -- Radiotherapy.
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Evidence-based medicine.
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Health care teams.
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Head and Neck Neoplasms -- therapy |
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Neoplasm Recurrence, Local -- therapy |
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Chemoradiotherapy |
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Evidence-Based Medicine |
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Patient Care Team |
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Médecine factuelle.
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Soins médicaux -- Travail en équipe.
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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Health care teams
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Evidence-based medicine
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Head -- Cancer -- Radiotherapy
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| Added Author |
Mehanna, Hisham M., editor.
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Ang, K. K. (K. Kian), editor.
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| Other Form: |
Print version: Head and neck cancer recurrence. Stuttgart : Thieme, 2012 9783131473912 (DLC) 2012019185 (OCoLC)785080324 |
| ISBN |
9783131645715 (electronic bk.) |
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3131645717 (electronic bk.) |
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9781283638838 (MyiLibrary) |
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1283638835 (MyiLibrary) |
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9783131473912 |
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3131473916 |
| Standard No. |
AU@ 000058064908 |
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DEBSZ 493117121 |
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