| Description |
1 online resource (viii, 394 pages) : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Summary |
In the past ten years there has been a rapid growth of the research and application area known as Lab-on-a-Chip. After an initial focus on electrokinetic separation techniques on chip, the scope of the field has widened to include topics like microfluidics, DNA analysis, cell analysis, microreactors and mass spectrometer interfacing. As well as the analytical chemistry community, synthetic chemists, chemical engineers, biochemists and biomedical engineers are now also becoming more and more interested in using new micro- and nanotechnological techniques. This first Lab-on-a-Chip book contains a broad collection of papers on microtechnology, microfluidics, analytical methods and applications. All contributions are written by leading researchers in their respective fields, and provide new scientists with an overview of the field, to make him/her aware of the enormous opportunities offered by modern technology. The work presented in this book will definitely stimulate readers to new ideas and concepts, and lead to further innovations in this area. - Provides a quick introduction into the different aspects of this field - Describes technology that has already revolutionized the world of chemical and biochemical analysis and synthesis - All contributions are written by leading researchers in their respective fields. |
| Contents |
I TECHNOLOGIES -- Hydrogels and polymers as components of a lab on a chip -- Microreplication technologies for polymer-based æTAS applications -- Silicon and glass micromachining for æTAS -- Surface chemistry in polymer microfluidic systems -- Plastic microfluidic devices: electrokinetic manipulations, life science applications, and production technologies -- II METHODS -- Transverse diffusion in microfluidic systems -- Nanoliter & picoliter liquid handling -- Micro sequential injection system for monitoring of metabolites extruded by cultured cells -- III CELL- & BEAD-BASED SYSTEMS -- Handling of beads in microfluidic devices for biotech applications -- Particles and molecules handling in micro channels -- Cell counting and cell sizing in microstructures -- IV APPLICATIONS -- Microfabricated capillary array electrophoresis: -- implementation and applications -- Microfluidic systems for analysis of the proteome with mass spectrometry -- Interfacing æTAS to matrix assisted laser desorption time-of-flight masspectrometry -- MALDI-TOF MS -- Micro integrated chemical systems for general use -- Synthesis in micro reactors using electro-osmotic flow -- Biochips aiming at advanced medical treatment -- BioMEMS for drug delivery applications. |
| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Subject |
Microchemistry -- Equipment and supplies.
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Fluidic devices.
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Micromechanics.
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Analytical biochemistry.
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Dispositifs fluidiques.
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Micromécanique.
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Biochimie analytique.
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TECHNOLOGY & ENGINEERING -- Chemical & Biochemical.
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SCIENCE -- Chemistry -- Industrial & Technical.
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Analytical biochemistry
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Fluidic devices
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Microchemistry -- Equipment and supplies
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Micromechanics
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| Added Author |
Oosterbroek, R. Edwin.
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Berg, A. van den (Albert)
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| Added Title |
Miniaturized systems for biochemical analysis and synthesis |
| Other Form: |
Print version: Lab-on-a-chip. Amsterdam ; Boston : Elsevier, 2003 9780444511003 (DLC) 2004295030 (OCoLC)53376716 |
| ISBN |
9780444511003 (electronic bk.) |
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0444511008 (electronic bk.) |
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9780080509884 (electronic bk.) |
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0080509886 (electronic bk.) |
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1282344978 |
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9781282344976 |
| Standard No. |
AU@ 000055615463 |
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CHDSB 005988941 |
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DEBBG BV042313759 |
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DEBSZ 367767694 |
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DEBSZ 430804520 |
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NZ1 12434137 |
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