1. History of malaria and its treatment 2. Knowing one's enemy: the Plasmodium parasite 3. The cinchona alkaloids and the aminoquinolines 4. Artemisinin and artemisinin-related agents 5. Agents acting on pyrimidine metabolism 6. Antimalarial agents acting on hemoglobin degradation 7. Plasmepsins as targets for antimalarial agents 8. Falcipains as drug targets in antimalarial therapy 9. Drug targets in the apicoplast 10. Drugs targeting mitochondrial functions 11. The Plasmodium falciparum proteasome as a drug target 12. Transferases and their inhibition 13. Kinases and kinase inhibitors 14. Miscellaneous agents of clinical interest 15. Inhibitors of purine and pyrimidine pathways 16. Miscellaneous targets
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