| Description |
xvii, 205 pages : illustrations ; 24 cm |
|
text txt rdacontent |
|
unmediated n rdamedia |
|
volume nc rdacarrier |
|
University and college faculty members Indians (India) Environmentalists lcdgt |
| Bibliography |
Includes bibliographical references (pages 179-194) and index. |
| Contents |
Preface -- 1. Breeding a Perfect Society ; Beginnings: Davenport and eugenics in the United States ; IQ and involuntary sterilization ; Genetics against eugenics ; Exporting sterilization ; The Watson scandal ; Establishing human genetics ; Davenport's dreams today -- 2. Molecular Diseases, Elusive Treatments ; The molecularization of biology ; Molecular diseases ; But no molecular medicine ; Dreams of editing genes ; Followed by stunning failure ; Recombinant DNA made no difference ; Gene editing BC (efore CRISPR) -- 3. What Good Was the Human Genome Project? ; The sequence revealed ; Common diseases and common variants ; Medical irrelevance of the sequence ; Critiques of the HGP, past and present ; Evolution and architecture of the genome ; Evolutionary contingency -- 4. The CRISPR Revolution ; The CRISPR structure emerges ; Its function is decoded ; The mechanism of immunity ; Onward to gene editing ; The delivery problem ; Ubiquitous CRISPR -- 5. Inevitable Eugenics? ; Eugenics in the news ; What is eugenics? ; Defining eugenics ; A working definition ; Inescapable eugenics? ; Matters of ethics -- 6. Eliminating Genetic Diseases ; The long reach of Huntington's disease ; The He Jiankui affair ; The ethics of human germline intervention ; The limits of current science ; Gene specificity and Lenin's brain ; A policy proposal ; Proceed with caution ; Liberal and moderate eugenics -- 7. Designer Baby Delusions ; Why not genetic enhancement? ; The normal and the enhanced ; Liberal eugenics and genetic enhancement ; Rationality of genetic enhancement ; Planned human obsolescence ; Where is the science? The case of intelligence ; Genomics and IQ ; What about physical traits ; Genetic reductionism ; Contextual developmental construction ; What is perfection? -- 8. A CRISPR Future ; Editing the human germline ; Gene drives ; The ethics of promoting extinction ; Biosecurity ; CRISPR without the hype. |
| Summary |
"Bringing together historical and ethical insights on the revolutionary, Nobel prize winning CRISPR/Cas9 gene editing technology, this accessible book examines the history of human attempts to understand and control our evolution, how the CRISPR/Cas9 technology works and what it could mean for the elimination of genetic diseases"-- Provided by publisher. |
| Subject |
Gene editing.
|
|
Gene editing -- Moral and ethical aspects.
|
|
CRISPR-associated protein 9.
|
|
CRISPR-associated protein 9. (OCoLC)fst02000537
|
|
Gene editing. (OCoLC)fst02000662
|
| ISBN |
9781786614377 (hardcover ; alkaline paper) |
|
1786614375 (hardcover ; alkaline paper) |
|
9781786614391 electronic publication |
|
