| Description |
1 online resource (252 pages) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
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text file PDF rda |
| Note |
Print version record. |
| Contents |
Preface; Acknowledgments; 1 Introduction; 2 Peritoneal carcinomatosis: a neglected disease; 2.1 An unmet medical need; 2.2 Role of the physician in provision of care in advanced peritoneal cancer; 2.3 Palliative care in peritoneal carcinomatosis; 3 Normal and diseased peritoneum; 3.1 Ontology; 3.2 Anatomy; 3.2.1 Blood supply; 3.2.2 Lymphatics; 3.2.3 Lymphatic stomata; 3.2.4 Milky spots; 3.2.5 Greater omentum; 3.2.6 Peritoneal nerves; 3.3 Physiology of peritoneum; 3.3.1 Peritoneum-plasma barrier; 3.3.2 Intraperitoneal Hydrostatic Pressure; 3.4 Pathophysiology of peritoneal carcinomatosis. |
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3.4.1 Epithelial-mesenchymal transition3.4.2 Interstitial intratumoral fluid pressure; 3.4.3 Ascites; 3.4.4 Hormonal changes; 4 Diagnosis and staging of peritoneal carcinomatosis; 4.1 Diagnostic workup; 4.2 Imaging studies; 4.2.1 Computer tomography (CT scan); 4.2.2 Magnetic Resonance Imaging (MRI); 4.2.3 Ultrasound; 4.2.4 FDG-Positron emission tomography (PET); 4.3 Diagnostic laparoscopy; 4.3.1 Peritoneal Cancer Index; 4.4 Peritoneal or pleural cytology; 4.4.1 Gastric cancer; 4.4.2 Ovarian cancer; 4.4.3 Colorectal cancer; 5 Therapy of peritoneal carcinomatosis. |
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5.1 Systemic palliative chemotherapy5.2 Intraperitoneal chemotherapy; 5.3 Drug uptake into tumoral tissue; 5.3.1 Diffusion; 5.3.2 Convection; 5.4 Effect of peritonectomy on drug clearance; 5.5 Influence of intraperitoneal drug concentration; 5.6 Tissue penetration of various drugs; 5.6.1 Doxorubicin (see also page 199); 5.6.2 Cisplatinum (see also page 198); 5.6.3 Oxaliplatinum; 5.6.4 Taxanes (Paclitaxel, Docetaxel); 5.7 Perioperative intraperitoneal chemotherapy; 5.7.1 CHPP; 5.7.2 NIPS; 5.7.3 EIPL; 5.7.4 EPIC; 5.8 Intraperitoneal chemotherapy for ascites. |
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5.9 Limitations of intraperitoneal chemotherapy5.9.1 Poor drug penetration; 5.9.2 Poor surface exposition; 5.9.3 Local toxicity; 5.9.4 Peritoneal sclerosis; 5.10 Intraperitoneal immunotherapy; 5.10.1 Catumaxomab; 5.10.2 Bevacizumab; 5.10.3 Immunoradiotherapy; 5.11 Intraperitoneal cytolytic virotherapy; 5.12 Nanodrugs; 5.13 Combined CRS with HIPEC; 5.13.1 Cytoreductive surgery (CRS); 5.13.2 Hyperthermic IntraPEritoneal Chemotherapy (HIPEC); 5.13.3 Colorectal cancer; 5.13.4 Ovarian Cancer; 5.13.5 Gastric Cancer; 5.13.6 Learning curve and expertise; 5.13.7 Evidence of cost effectiveness. |
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5.13.8 Safety5.13.9 Indications for CRS and HIPEC; 6 Assessing tumor response in peritoneal carcinomatosis; 6.1 Natural history of peritoneal carcinomatosis; 6.2 RECIST criteria; 6.2.1 RECIST criteria in peritoneal carcinomatosis; 6.3 Laparoscopy in peritoneal carcinomatosis; 6.4 Histology for determining tumor response; 6.5 Tumor markers for determining tumor response; 6.5.1 Gastric cancer; 6.5.2 Ovarian cancer; 6.5.3 Colorectal cancer; 6.6 Determining clinical benefit rate in peritoneal carcinomatosis; 7 Principle of therapeutic capnoperitoneum; 7.1 Material and methods. |
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7.1.1 Design of the prototype. |
| Summary |
<!Doctype html public ""-//w3c//dtd html 4.0 transitional//en""> <html><head> <meta content=""text/html; charset=iso-8859-1"" http-equiv=content-type> <meta name=generator content=""mshtml 8.00.6001.23543""></head> <body> Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach for treating peritoneal carcinomatosis. First encouraging results have been obtained in human patients. </body></html> |
| Bibliography |
Includes bibliographical references at the end of each chapters and index. |
| Language |
In English. |
| Subject |
Antineoplastic agents.
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Aerosol.
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Antineoplastic Combined Chemotherapy Protocols |
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Peritoneal Neoplasms -- drug therapy |
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Aerosols -- therapeutic use |
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Carcinoma -- drug therapy |
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Anticancéreux.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Antineoplastic agents
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Peritonealkarzinose
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Pressurized Intraperitoneal Aerosol Chemotherapy
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| Genre/Form |
Aufsatzsammlung.
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| Added Author |
Solass, Wiebke.
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| Other Form: |
Print version: Reymond, Marc A. PIPAC : Pressurized IntraPeritoneal Aerosol Chemotherapy - Cancer under Pressure. Berlin/Boston : De Gruyter, ©2014 9783110345940 |
| ISBN |
9783110366624 (electronic bk.) |
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3110366622 (electronic bk.) |
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9783110386363 |
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3110386364 |
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3110366614 |
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9783110366617 |
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9783110366617 |
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3110366614 |
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3110345943 |
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9783110345940 |
| Standard No. |
10.1515/9783110366617 doi |
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9783110386363 |
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urn:nbn:de:101:1-201605268680 urn |
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9783110366617 |
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urn:nbn:de:101:1-201609198266 urn |
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AU@ 000056056997 |
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DEBBG BV042524664 |
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DEBBG BV044068389 |
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DEBSZ 433286156 |
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DEBSZ 43481122X |
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GBVCP 813263662 |
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GWDNB 1101864389 |
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GWDNB 1114101583 |
