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Title Antiviral drug strategies / edited by Erik De Clercq.

Imprint Weinheim : Wiley-VCH, c2011.


Location Call No. OPAC Message Status
 Axe 2nd Floor Stacks  615.7924 An87 2011    ---  Available
Description xx, 406 p. : ill. ; 25 cm.
Series Methods and principles in medicinal chemistry ; v. 50
Methods and principles in medicinal chemistry ; v. 50.
Bibliography Includes bibliographical references and index.
Contents Outlook of the antiviral drug era, now more than 50 years after description of the first antiviral drug / Erik De Clercq -- Inhibition of HIV entry / Jose A. Este -- Targeting integration beyond strand transfer: development of second-generation HIV integrase inhibitors / Arnout R. D. Voet, Marc De Maeyer, Frauke Christ, Zeger Debyser -- From saquinavir to darunavir: the impact of 10 years of medicinal chemistry on a lethal disease / Marie-Pierre de Bethune, Anik Peeters, Piet Wigerinck -- Acyclic and cyclic nucleoside phosphonates / Richard L. Mackman, Tomas Cihlar -- Helicase-primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus / Subhajit Biswas, Hugh J. Field -- Cyclophilin inhibitors / Gregoire Vuagniaux, Arnaud Hamel, Rafael Crabbe, Herve C. Porchet, Jean-Maurice Dumont -- Alkoxyalkyl ester prodrugs of antiviral nucleoside phosphates and phosphonates / James R. Beadle, Karl Y. Hostetler -- Maribavir: a novel benzimidazole ribonucleoside for the prevention and treatment of cytomegalovirus diseases / Karen K. Biron -- Anti-HCMV compounds / Graciela Andrei, Robert Snoeck -- Lethal mutagenesis as an unconventional approach to combat HIV / Pinar Iyidogan, Karen S. Anderson -- Recent progress in the development of HCV protease inhibitors / Nagraj Mani, Bhisetti G. Rao, Tara L. Kieffer, Ann D. Kwong -- Antiviral RNAi: how to silence viruses / Karin J. von Eije, Ben Berkhout -- Neuraminidase inhibitors as anti-influenza agents / Willard Lew, Michael Z. Wang, Xiaowu Chen, James F. Rooney, Choung Kim -- From TIBO to rilpivirine: the chronicle of the discovery of the ideal nonnucleoside reverse transcriptase inhibitor / Erik De Clercq.
Subject Antiviral agents -- Development.
Antiviral Agents.
Drug Discovery.
Added Author De Clercq, Erik.
ISBN 9783527326969 (hbk. : alk. paper)
3527326960 (hbk. : alk. paper)

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