| Description |
1 online resource. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Woodhead Publishing Series in Biomaterials |
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Woodhead Publishing series in biomaterials.
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| Summary |
The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material's surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone. The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performanceStudies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topographyDiscusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection. |
| Contents |
Cover; Surface modification of biomaterials: Methods, analysis and applications; Copyright; Contents; Contributor contact details; Preface; Part I Surface modification techniques; 1 Surface modification of biomaterials by plasma polymerization; 1.1 Introduction; 1.2 An overview of plasma and plasma polymerization; 1.3 Plasma generation and systemdesign; 1.4 Plasma parameters; 1.5 Intrinsic parameters; 1.6 Potential biomaterial applications; 1.7 Future trends in plasma polymers; 1.8 Sources of further information and advice; 1.9 References. |
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2 Surface modification of biomaterials by covalent binding of poly(ethylene glycol) (PEG)2.1 Introduction; 2.2 Principles andmethods; 2.3 Technologies and applications; 2.4 Conclusions and future trends; 2.5 References; 3 Surface modification of biomaterials by heparinisation to improve blood compatibility; 3.1 Introduction; 3.2 Bioactivemolecule: heparin; 3.3 Blood-biomaterial interaction; 3.4 Surface modification by heparinisation for improved blood compatibility; 3.5 Future trends in heparinisation of biomaterial surfaces; 3.6 References. |
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4 Surface modification of biomaterials by peptide functionalisation4.1 Introduction; 4.2 Peptides and peptide functionalisation of surfaces; 4.3 Defining the biomaterial surface; 4.4 Peptide functionalised surfaces; 4.5 Non-covalent peptide functionalisation by self-assembly; 4.6 Spatial control of peptide functionality; 4.7 Conclusions; 4.8 References; 5 Metal surface oxidation and surface interactions; 5.1 Surface oxides inmetallic medical devices: the scenario. |
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5.2 Titaniumoxides on Ti implants: from crystallographic structure to the theoretical study of the atomistic surface structure and behaviour5.3 Technologies for tailoring Ti oxides on titanium; 5.4 Future trends; 5.5 References; 5.6 Appendix A: Materials andmethods for unpublished results; 5.7 Appendix B: Abbreviations and symbols; 6 Surface modification of biomaterials by calcium phosphate deposition; 6.1 Introduction; 6.2 Basicmethods and applications; 6.3 Strengths and weaknesses; 6.4 Future trends; 6.5 Sources of further information and advice; 6.6 References. |
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7 Biomaterial surface topography to control cellular response: technologies, cell behaviour and biomedical applications7.1 Introduction; 7.2 Defining micron and nano; 7.3 Manufacturing surface topography; 7.4 Howsurface topography affects cell behaviour; 7.5 Technologies and potential applications; 7.6 Tissue regeneration; 7.7 Current issues and future trends; 7.8 Acknowledgements; 7.9 References; Part II Analytical techniques and applications; 8 Techniques for analysing biomaterial surface chemistry; 8.1 Introduction; 8.2 X-ray photoelectron spectroscopy (XPS). |
| Subject |
Biomedical materials -- Surfaces.
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Biomatériaux -- Surfaces.
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HEALTH & FITNESS -- Holism.
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HEALTH & FITNESS -- Reference.
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MEDICAL -- Alternative Medicine.
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MEDICAL -- Atlases.
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MEDICAL -- Essays.
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MEDICAL -- Family & General Practice.
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MEDICAL -- Holistic Medicine.
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MEDICAL -- Osteopathy.
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Biomedical materials -- Surfaces
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| Added Author |
Williams, Rachel.
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| Other Form: |
Print version: Williams, R. Surface Modification of Biomaterials : Methods Analysis And Applications. Burlington : Elsevier Science, ©2010 9781845696405 |
| ISBN |
9780857090768 (electronic bk.) |
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0857090763 (electronic bk.) |
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9781845696405 |
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1845696409 |
| Standard No. |
DEBBG BV042316724 |
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DEBSZ 414262557 |
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GBVCP 800005724 |
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NZ1 15319476 |
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NZ1 15583069 |
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AU@ 000061137906 |
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AU@ 000055775829 |
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