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Title Medical applications of mass spectrometry / edited by Károly Vékey, András Telekes, Akos Vertes.

Imprint Amsterdam ; Boston : Elsevier, 2008.


Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Edition 1st ed.
Description 1 online resource (xxiii, 581 pages) : illustrations
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Summary Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine. The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry. * Guides the reader from basic principles and methods to cutting edge applications. * There is NO comparable book on the market to fill this fast growing field.
Contents 1. Introduction 2. Basics of analytical chemistry and mass spectrometry for medical professionals 3. Ethical, legal, safety and scientific aspects of medical research 4. Biomedical sampling 5. Separation methods 6. Mass spectrometry instrumentation and techniques 7. Cheminformatics: multivariate mathematical-statistical methods for data evaluation 8. Mass spectrometry in proteomics 9. De novo sequencing of peptides 10. Protein bioinformatics 11. Analysis of complex lipidomes 12. Medical laboratory practice -- possibilities for mass spectrometry 13. Therapeutic drug monitoring 14. Mass spectrometry of infectious pathogens 15. Proteomics of viruses and their host partners 16. Neonatal diagnostics 17. Application of mass spectrometry in oncology -- 18 Application of mass spectrometry in brain research: neurotransmitters, neuropeptides and brain proteins 19. The human pituitary proteome: clinical applications 20. Mass spectrometry of proteinous allergens inducing human diseases 21. Mass spectrometry in clinical treatment 22. Biomarker discovery 23. Molecular imaging by mass spectrometry 24. Brief outlook.
Bibliography Includes bibliographical references and index.
Note Print version record.
Language English.
Subject Mass spectrometry.
Spectrum analysis -- Diagnostic use.
Mass Spectrometry
Spectrométrie de masse.
Analyse spectrale -- Utilisation diagnostique.
mass spectrometry.
SCIENCE -- Chemistry -- Analytic.
Mass spectrometry
Spectrum analysis -- Diagnostic use
Genre/Form dissertations.
Academic theses
Academic theses.
Thčses et écrits académiques.
Added Author Vékey, Károly.
Telekes, András.
Vertes, Akos, 1952-
Other Form: Print version: Medical applications of mass spectrometry. 1st ed. Amsterdam ; Boston : Elsevier, 2008 9780444519801 0444519807 (OCoLC)144227390
ISBN 9780444519801
9780080554655 (electronic bk.)
0080554652 (electronic bk.)
Standard No. AU@ 000043178391
AU@ 000051563172
AU@ 000059270139
CHDSB 005985661
DEBBG BV042305665
DEBBG BV043045228
DEBSZ 36776718X
DEBSZ 422161489
NZ1 12541532
NZ1 14540456
NZ1 15189583

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