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Author Stein, Ross L.

Title Kinetics of enzyme action [electronic resource] : essential principles for drug hunters / Ross L. Stein.

Imprint Hoboken, N.J. : Wiley, c2011.


Location Call No. OPAC Message Status
 Axe ProQuest E-Book  Electronic Book    ---  Available
Description xii, 302 p. : ill.
Bibliography Includes bibliographical references and index.
Contents Kinetics of single-substrate enzymatic reactions -- Kinetics of single-substrate enzymatic reactions : special topics -- Enzyme inhibition : the phenomenon and mechanistic analysis -- Kinetic mechanism of inhibition of one-substrate enzymatic reactions -- Tight-binding, slow-binding, and irreversible inhibitors -- Kinetics of two-substrate enzymatic reactions -- Kinetic mechanism of inhibition of two-substrate enzymatic reactions -- Allosteric modulation of enzyme-catalyzed reactions -- Kinetics-based probes of enzyme mechanisms.
Summary "Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery"--Provided by publisher.
Reproduction Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
Subject Enzymes -- Pharmacokinetics.
Enzyme inhibitors -- Pharmacokinetics.
Genre/Form Electronic books.
Added Author ProQuest (Firm)
ISBN 9780470414118 (cloth)
9781118084410 (oIBSN)
9781118084403 (ePub)
9781118084397 (e-book)

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