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Author Schiesser, W. E., author.

Title ODE/PDE [alpha]-synuclein models for Parkinson's disease / W.E. Schiesser.

Publication Info. London [England] : Academic Press, [2018]


Location Call No. OPAC Message Status
 Axe Elsevier ScienceDirect Ebook  Electronic Book    ---  Available
 Axe Elsevier ScienceDirect Ebook    ---  Available
Description 1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Bibliography Includes bibliographical references and index.
Note Online resource; title from PDF title page (EBSCO, viewed February 20, 2018).
Summary ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein?-synuclein, a monomer that has been implicated in this disease. Specifically,?-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the?-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms.
Subject Parkinson's disease -- Mathematical models.
Parkinson Disease
Models, Neurological
Maladie de Parkinson -- Modèles mathématiques.
Maladie de Parkinson.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Alpha-synuclein. (OCoLC)fst01896510
Genre/Form Electronic books.
ISBN 9780128148020 (electronic bk.)
0128148020 (electronic bk.)
Standard No. AU@ 000062123126

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