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Title Analysis of aggregates and particles in protein pharmaceuticals [electronic resource] / edited by Hanns-Christian Mahler, Wim Jiskoot.

Imprint Hoboken, N.J. : John Wiley & Sons, Inc., 2012.

Copies

Location Call No. OPAC Message Status
 Axe ProQuest E-Book  Electronic Book    ---  Available
Description xvi, 443 p., [12] p. of plates : ill. (some col.)
Bibliography Includes bibliographical references.
Contents The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles.
Reproduction Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
Subject Pharmaceutical chemistry.
Protein drugs -- Analysis.
Genre/Form Electronic books.
Added Author Mahler, Hanns-Christian.
Jiskoot, Wim.
ProQuest (Firm)
ISBN 9780470497180 (cloth)
9781118150542 (e-book)

 
    
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