Description |
xvi, 443 p., [12] p. of plates : ill. (some col.) |
Bibliography |
Includes bibliographical references. |
Contents |
The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles. |
Reproduction |
Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. |
Subject |
Pharmaceutical chemistry.
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Protein drugs -- Analysis.
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Genre/Form |
Electronic books.
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Added Author |
Mahler, Hanns-Christian.
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Jiskoot, Wim.
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ProQuest (Firm)
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ISBN |
9780470497180 (cloth) |
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9781118150542 (electronic bk.) |
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