This book provides a hybrid methodology for engineering of trickle bed reactors by integrating conventional reaction engineering models with state-of-the-art computational flow models. The content may be used in several ways and at various stages in the engineering process: it may be used as a basic resource for making appropriate reactor engineering decisions in practice; as study material for a course on reactor design, operation, or optimization of trickle bed reactors; or in solving practical reactor engineering problems. Facilitates development of high fidelity models for industrial applications. Facilitates selection and application of appropriate models. Guides development and application of computational models to trickle beds.