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Author Gendelman, Howard E.

Title The Neurology of AIDS.

Imprint Oxford : Oxford University Press, USA, 2011.


Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Edition Third edition.
Description 1 online resource (1156 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Note Print version record.
Contents Cover; Contents; Contributors; Interactive Topical Discussion on AIDS Neurology: Past, Present, and Future; SECTION 1 HIV-1 BIOLOGY AND IMMUNOLOGY; 1.1 HIV-1 Biology; 1.2 HIV-1 Immunology; 1.3 Chemokines; 1.4 Viral and Host Genetic Factors; 1.5 Genetic Susceptibilities for NeuroAIDS; SECTION 2 INNATE AND CELLULAR IMMUNITY AND NEUROGENESIS; 2.1 Mononuclear Phagocytes; 2.2 Microglia; 2.3 Astrocytes; 2.4 Adaptive Immunity; 2.5 Vaccines; 2.6 Neurogenesis; SECTION 3 BLOOD-BRAIN BARRIER AND HIV CNS ENTRY; 3.1 Blood-Brain Barrier: Structure and Function.
3.2 Endothelial Cell Biology and HIV-1 Infection3.3 Blood-Brain Barrier during Neuroinflammation; 3.4 Mechanisms of Viral and Cell Entry into the Central Nervous System; 3.5 Monocyte-Macrophages and Viral Central Nervous System Entry; SECTION 4 CELLULAR AND VIRAL NEUROTOXICITY AND ABUSED DRUGS; 4.1 Mononuclear Phagocyte Inflammation and Neurotoxicity; 4.2 Neurotoxicity of HIV-1 Proteins; 4.3 HIV-1 and Tat: Neuropathogenesis and Therapeutic Targets; 4.4 HIV-1 gp120; 4.5 HIV-1 and Cannabinoids; 4.6 HIV-1 and Meth; 4.7 HIV-1 and Opioids; 4.8 HIV-1 and Cocaine; SECTION 5 ANIMAL MODELS.
5.1 Simian Immunodeficiency Virus5. 2 Feline Immunodeficiency Virus; 5.3 Caprine Arthritis Encephalitis Virus and Visna; 5.4 Transgenics; 5.5 Murine Models for NeuroAIDS; 5.6 Simian Immunodeficiency Virus and Opiates; 5.7 SIV and FIV Models of Peripheral Neuropathy; 5.8 Animal Models and Bioimaging; SECTION 6 PERSONAL PERSPECTIVES IN LIVING WITH HIV/AIDS; 6.1 HIV and My Mental Health -- A Personal Reflection; 6.2 Fear and Loathing in HIV Mental Health Care; 6.3 Memories; 6.4 HIV Dementia: A Patient's Perspective. Living with the Suffering, the Diagnosis, and the Uncertainties.
6.5 My Virus Just Turned Twenty-One: A Woman's Perspective of the Long-term Psychological Impact of Living with HIVSECTION 7 CLINICAL AND PATHOLOGIC MANIFESTATIONS OF DISEASE; 7.1 Perspective on HIV CNS Infections; 7.2 HIV-Associated Neurocognitive Disorders; 7.3 The CNS in Acute and Early Infection; 7.4 HIV-1 Neuropathology; 7.5 Peripheral Neuropathy; 7.6 Spinal Cord Disease; 7.7 Myopathy; 7.8 Aging; 7.9 Addiction; SECTION 8 PATHOGENESIS OF COMORBID CONDITIONS; 8.1 NeuroAIDS as an Inflammatory Disorder; 8.2 Neuronal Injury, White Matter Disease, and Neurotrophic Factors.
8.3 Pathobiology of HIV-related Neuropathies8.4 CNS Comorbidities; 8.5 Opportunistic Infections; 8.6 Progressive Multifocal Leukoencephalopathy; 8.7 Neoplasms; 8.8 Hepatitis C; 8.9 HIV and Psychiatric Comorbidities; SECTION 9 DIAGNOSTICS AND BIOMARKERS; 9.1 Bioimaging; 9.2 Magnetic Resonance Imaging; 9.3 Psychological Evaluations; 9.4 Viral and Cellular Biomarkers during Antiretroviral Therapy; 9.5 Viral Dynamics; 9.6 Viral Clades: Role in HIV Neuropathogenesis; 9.7 Proteomics and Biomarkers; SECTION 10 CHILDREN AND ADOLESCENTS.
Note 10.1 Clinical and Pathological Features of HIV-1 Encephalopathy in Children and Adolescents.
Summary Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric disease manifestations, concomitant drug abuse, neuropathies, and an inability to clear viral reservoirs, explain, in large measure, disease progression and immune deterioration. These are associated with a number of psychiatric, muscle, nerve, infectious, as well as cognitive, behavioral, and motor di.
Bibliography Includes bibliographical references and index.
Subject AIDS (Disease)
HEALTH & FITNESS -- Diseases -- AIDS & HIV.
AIDS (Disease) (OCoLC)fst00793808
Neurology. (OCoLC)fst01036390
Genre/Form Electronic books.
Added Author Grant, Igor, 1942-
Everall, Ian Paul.
Other Form: Print version: Gendelman, Howard E. Neurology of AIDS. Oxford : Oxford University Press, USA, 2011 9780195399349
ISBN 9780199875559
9780195399349 (hardcover alk. paper)

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