| Description |
1 online resource (ix, 286 pages) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Access |
Use copy Restrictions unspecified star MiAaHDL |
| Reproduction |
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL |
| System Details |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
| Processing Action |
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Note |
Print version record. |
| Contents |
Front Cover -- Carcinogenicity of Inorganic Substances: Risks from Occupational Exposure -- Copyright Page -- Table of Contents -- Preface -- Organizers, Sponsors, Members of the Scientific and Editorial Board and Steering Organizing Committee -- Setting the Scene: The Scientific Context -- Part 1: Scientific Presentations -- Chapter 1. General Overview of the Scientific Presentations -- 1 Bio-inorganic Chemistry -- 2 Physico-chemical Characterisation of Exposures -- 3 Experimental Studies -- 4 Epidemiological Studies |
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Chapter 2. Bio-inorganic Chemistry and Cancer1 The Essential Elements -- 2 Attack on DNA -- 3 Buffering and Homeostasis of Ions -- 4 Conclusion -- References -- Chapter 3. Physico-chemical Properties of Inorganic Particles Controlling Biological Activity -- 1 Introduction -- 2 Quantitative Description of Particle Morphology -- 3 Carcinogenicity of Fibrous Particles -- 4 Conclusions -- References -- Chapter 4. Mineralogical Factors and the Relationship of Fibres and Dusts in Humans to Disease -- 1 Introduction -- 2 Particles in the General Population |
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3 Fibre Burden and Disease Caused by AsbestosReferences -- Chapter 5. In Vitro Studies of Genotoxicity and their Significance -- 1 Introduction -- 2 Genotoxicity Studies -- 3 Cytotoxicity, Cell Viability -- 4 Present and Further Research Areas -- 5 Conclusions -- References -- Chapter 6. Sequence of Events in Lung Carcinogenesis -- 1 Interindividual Variation in Cancer Susceptibility -- 2 Field Cancerization Theory -- 3 Somatic Genetic Changes Commonly Detected in Lung Cancer -- 4 Putative Role For Autocrine Loops in the Development of Lung Cancer |
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5 Sequence of Events in Lung CarcinogenesisReferences -- Chapter 7. The Significance of Toxicokinetics of Solid Particles in the Rat Lung -- 1 Introduction -- 2 Design of Retention Measurements -- 3 Generic Response in Particle Inhalation Studies -- 4 Dust Overload in Lungs -- 5 Irreversibility of Clearance Retardation -- 6 Migration of Particles to Lung-associated Lymph Nodes -- 7 Model Calculation of Retention Kinetics of Solid Particles -- 8 The Concept of Maximum Tolerated Dose (MTD) in Chronic Inhalation Studies -- 9 Fibres -- 10 Quartz |
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11 Solid Ultrafine ParticlesReferences -- Chapter 8. Mechanisms and Significance of Particle Overload -- 1 Background -- 2 A Definition of Dust Overloading -- 3 Overload Studies -- 4 Particle Clearance Kinetics -- 5 Mechanistic Concepts -- 6 The Reversibility of Overload -- 7 Overload in Other Species -- 8 Does Dust Overload Pertain to Humans? -- 9 The Implications of Overload -- 10 Relatable Issues -- 11 Conclusions -- 12 Acknowledgement -- References |
| Subject |
Carcinogens -- Congresses.
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Cancer -- Etiology -- Congresses.
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Industrial toxicology -- Congresses.
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Carcinogens.
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Carcinogens |
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Neoplasms -- etiology |
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Occupational Exposure |
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Cancérogènes -- Congrès.
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Cancer -- Étiologie -- Congrès.
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Toxicologie industrielle -- Congrès.
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Cancérogènes.
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MEDICAL -- Pharmacology.
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Cancer -- Etiology
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Carcinogens
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Industrial toxicology
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Carcinoma.
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Toxicologia em area ocupacional.
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| Genre/Form |
Congress |
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proceedings (reports)
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Conference papers and proceedings
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Conference papers and proceedings.
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Actes de congrès.
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| Added Author |
Duffus, John H.
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| Other Form: |
Print version: International Seminar on Assessment of Carcinogenic Risk from Occupational Exposure to Inorganic Substances (1995 : Luxembourg). Carcinogenicity of inorganic substances. Cambridge : Royal Society of Chemistry, ©1997 (OCoLC)39159616 |
| ISBN |
9781782424413 (electronic bk.) |
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1782424415 (electronic bk.) |
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9781855738003 (electronic bk.) |
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1855738007 (electronic bk.) |
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0854044299 |
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9780854044290 |
| Standard No. |
AU@ 000056992791 |
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DEBBG BV042313714 |
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DEBSZ 41426164X |
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GBVCP 797007903 |
