| Description |
1 online resource (xiv, 299 pages) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Contents |
ADVANCES IN MEDICINE AND BIOLOGY ; ADVANCES IN MEDICINE AND BIOLOGY ; Contents; Preface; C. Elegans and Neurodegeneration in Caenorhabditis Elegans: Anatomy, Life Cycles and Biological Functions; 1. Introduction; 2. Alzheimer's Disease; Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes; Chemical- and Metal-Induced Neurodegeneration; Pharmacological Compounds and Neurodegeneration; 3. Parkinson's Disease; Disease-Linked Mutations and Neurodegeneration; Autosomal Dominant Genes; Autosomal Recessive Genes; Screens Identifying Modifier Genes. |
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Chemical- and Metal-Induced NeurodegenerationPharmacological Compounds and Neurodegeneration; 4. Huntington's Disease; Disease-Linked Mutations and Neurodegeneration; Expression of Isolated PolyQ; Expression of Htt N-Terminal Fragments; Screens Identifying Modifier Genes; Pharmacological Compounds and Neurodegeneration; 5. Amyotrophic Lateral Sclerosis (ALS); Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes; 6. Spinal Muscular Atrophy (SMA); Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes. |
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Pharmacological Compounds and NeurodegenerationConclusions; Acknowledgments; References; Caenorhabditis elegans as a Host Model for Studying the Pathogenicity and Virulence of Staphylococcus aureus; Abstract; Introduction; Staphylococcus aureus and MRSA; S. aureus Virulence and Pathogenicity; Animal Models for S. aureus; Biology of C. elegans; Worm Anatomy and Life Cycle; C. elegans Defense Mechanism; C. elegans as a Host Model for Studying Bacterial Pathogenesis; C. elegans as a Host Model for Studying S. aureus Pathogenesis. |
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The C. elegans Host Model Correlates with Clinical Manifestations of S. aureus Infections in a Large Canadian Health Care RegionMRSA Strains with Distinct Nematocidal Activities Have Different; Genetic Backgrounds; Validation of the C. elegans Model Using Canadian Major Epidemic; MRSA Strains; Validation of the C. elegans Host Model in a Neonatal Intensive Care Unit (NICU) Outbreak in Toronto; MSSA Strains with Distinct Nematocidal Activities Have Different Genetic Backgrounds; Accumulation of S. aureus inside the Digestive Tract Is Correlated with Nematocidal Activity. |
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S. aureus Lysozyme Resistance Contributes S. aureus Lysozyme Resistance ContributesA Lysozyme-Sensitive S. aureus Mutant Exhibited Reduced Accumulation inside the C. elegans Gut; Mutation of Lysozyme Genes in C. elegans Reduced Nematodes Fitness against S. aureus; Conclusion; References; Understanding the Molecular Basis for the Hazards Associated with Nevirapine Treatment; Abstract; Overview; Nevirapine Pharmacokinetics and Metabolism; Nevirapine Toxicity; Nevirapine Bioactivation; Synthetic Biomarkers as Tools for Biomonitoring Nevirapine Toxicity; Acknowledgments; References. |
| Subject |
Clinical medicine.
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Biology.
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Clinical Medicine |
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Biology |
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Médecine clinique.
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Biologie.
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biology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Biology
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Clinical medicine
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| Added Author |
Berhardt, Leon V.
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| Other Form: |
Print version: Advances in medicine & biology. Volume 44. Hauppauge, N.Y. : Nova Science ; Lancaster : Gazelle [distributor], 2012 9781621009092 (OCoLC)775029473 |
| ISBN |
9781621009610 (electronic bk.) |
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1621009610 (electronic bk.) |
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9781621009092 |
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1621009092 |
| Standard No. |
DEBBG BV041049541 |
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DEBBG BV043775266 |
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DEBSZ 472777238 |
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