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Title Drug-drug interactions in pharmaceutical development / edited by Albert P. Li.

Imprint Hoboken, N.J. : Wiley-interscience, ©2008.


Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource (xiv, 244 pages, [1] pages) : illustrations (some color)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
data file rda
Series Wiley series in drug discovery and development
Wiley series in drug discovery and development.
Bibliography Includes bibliographical references and index.
Contents In vitro evaluation of metabolic drug-drug interactions: concepts and practice / Albert P. Li -- In vitro approaches to anticipating clinical drug interactions / Laurie P. Volak, David J. Greenblatt, Lisa L. von Moltke -- Inhibition of drug metabolizing enzymes and drug-drug interactions in drug discovery and development / R. Scott Obach -- Mechanism-based CYP inhibition: enzyme kinetics, assays, and prediction of human drug-drug interactions / Magang Shou -- Genomic approaches to drug-drug interactions / Yi Yang, Jeffrey F. Waring -- Transporters and drug interactions / Yoshihisa Shitara, Toshiharu Horie, and Yuichi Sugiyama -- Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin -- Recent case studies of clinically significant drug-drug interactions and the limits of in vitro prediction methodology / R.H. Levy, I. Ragueneau-Majlessi, C. Collins -- US regulatory perspective: drug-drug interactions / John Strong and Shiew-Mei Huang -- Herbal drug interactions: a Canadian perspective / Brian C. Foster.
Note Print version record.
Summary Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage.
Language English.
Subject Drug interactions.
Drug development.
Drug Interactions.
Chemistry, Pharmaceutical.
Interactions médicamenteuses.
MEDICAL -- Pharmacology.
Drug development. (OCoLC)fst00898670
Drug interactions. (OCoLC)fst00898681
Genre/Form Electronic books.
Electronic books.
Added Author Li, A. P.
Other Form: Print version: Drug-drug interactions in pharmaceutical development. Hoboken, N.J. : Wiley-interscience, ©2008 (DLC) 2007015878
ISBN 9780470187913 (electronic bk.)
0470187913 (electronic bk.)
9780471794417 (cloth)
0471794414 (cloth)
Standard No. 10.1002/9780470187920 doi
AU@ 000043398316
AU@ 000051544877
CHNEW 000935367
CHVBK 480157111
DEBBG BV043146671
DEBBG BV043391197
DEBBG BV044134602
DEBSZ 422015709
DEBSZ 484983059
NZ1 13340219

Available items only