| Description |
1 online resource (xiv, 244 pages, [1] pages) : illustrations (some color) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
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data file rda |
| Series |
Wiley series in drug discovery and development |
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Wiley series in drug discovery and development.
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| Bibliography |
Includes bibliographical references and index. |
| Contents |
In vitro evaluation of metabolic drug-drug interactions: concepts and practice / Albert P. Li -- In vitro approaches to anticipating clinical drug interactions / Laurie P. Volak, David J. Greenblatt, Lisa L. von Moltke -- Inhibition of drug metabolizing enzymes and drug-drug interactions in drug discovery and development / R. Scott Obach -- Mechanism-based CYP inhibition: enzyme kinetics, assays, and prediction of human drug-drug interactions / Magang Shou -- Genomic approaches to drug-drug interactions / Yi Yang, Jeffrey F. Waring -- Transporters and drug interactions / Yoshihisa Shitara, Toshiharu Horie, and Yuichi Sugiyama -- Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin -- Recent case studies of clinically significant drug-drug interactions and the limits of in vitro prediction methodology / R.H. Levy, I. Ragueneau-Majlessi, C. Collins -- US regulatory perspective: drug-drug interactions / John Strong and Shiew-Mei Huang -- Herbal drug interactions: a Canadian perspective / Brian C. Foster. |
| Note |
Print version record. |
| Summary |
Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage. |
| Language |
English. |
| Subject |
Drug interactions.
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Drug development.
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Drug Interactions. |
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Chemistry, Pharmaceutical. |
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Interactions médicamenteuses.
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MEDICAL -- Pharmacology.
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Drug development. (OCoLC)fst00898670
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Drug interactions. (OCoLC)fst00898681
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Arzneimittelentwicklung
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Arzneimittelwechselwirkung
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| Genre/Form |
Electronic books.
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Electronic books.
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| Added Author |
Li, A. P.
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| Other Form: |
Print version: Drug-drug interactions in pharmaceutical development. Hoboken, N.J. : Wiley-interscience, ©2008 (DLC) 2007015878 |
| ISBN |
9780470187913 (electronic bk.) |
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0470187913 (electronic bk.) |
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9780470187920 |
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0470187921 |
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9780471794417 (cloth) |
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0471794414 (cloth) |
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1282022067 |
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9781282022065 |
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9786612022067 |
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661202206X |
| Standard No. |
10.1002/9780470187920 doi |
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AU@ 000043398316 |
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AU@ 000051544877 |
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CHNEW 000935367 |
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CHVBK 480157111 |
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DEBBG BV043146671 |
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DEBBG BV043391197 |
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DEBBG BV044134602 |
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DEBSZ 422015709 |
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DEBSZ 484983059 |
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NZ1 13340219 |
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