| Description |
1 online resource (xii, 232 pages : illustrations). |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Neurodegenerative Diseases : Laboratory and Clinical Research |
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Neurodegenerative diseases--laboratory and clinical research.
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| Bibliography |
Includes bibliographical references and index. |
| Note |
Print version record. |
| Contents |
""PARKINSON'S DISEASE ""; ""PARKINSON'S DISEASE ""; ""CONTENTS ""; ""PREFACE ""; ""THERAPEUTIC INTERVENTION AT CELLULAR CLEARANCE MECHANISMS: SIGNIFICANCE TO PARKINSON�S DISEASE ""; ""ABSTRACT ""; ""ABBREVIATIONS ""; ""1. INTRODUCTORY REMARKS ""; ""2. INTRACELLULAR CLEARANCE MECHANISMS ""; ""2.1. The Ubiquitin Proteasome System ""; ""2.1.1. Quality Control through the Ubiquitin Proteasome System ""; ""2.1.2. Ubiquitin Proteasome System impairment in PD ""; ""2.2. The Autophagy-Lysosomal Pathway ""; ""2.2.1. Quality Control through the Autophagic- Lysosomal Pathway "" |
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""2.2.2. Autophagy- Lysosomal Pathway dysfunction in PD """"2.3. Enzymatic Proteolytic Systems ""; ""2.3.1. Quality Control through Cytosolic Proteolysis: Calpains ""; ""2.3.2. Quality Control through Mitochondrial Proteolysis: Lon, Clp-Like, AAA-Proteases ""; ""2.3.3. Enzymatic Proteolysis Disruption in PD ""; ""3. THERAPEUTIC INTERVENTIONS BASED ON THE MODULATION OF CLEARANCE MECHANISMS ""; ""3.1. Proteasomal Clearance � A Target for Therapeutic Intervention ""; ""3.2. Autophagic Clearance � A Target for Therapeutic Intervention "" |
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""3.3. Proteases Clearance � A Target for Therapeutic Intervention """"CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES""; ""PARKINSON�S DISEASE RELATED CHANGES OF OSCILLATORY ACTIVITY IN DISCRIMINATION TASKS ""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. METHODS ""; ""2.1. Experimental Procedure""; ""2.2. Analysis ""; ""3. EXPERIMENTAL RESULTS ""; ""Early (0�250 ms) Post-stimulus Interval ""; ""Late (250�600 ms) Post-stimulus Interval ""; ""4. DISCUSSION ""; ""CONCLUSION ""; ""REFERENCES "" |
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""NEW INSIGHTS INTO THE MECHANISM OF SLOWING OF VOLUNTARY MOVEMENTS IN PARKINSON�S DISEASE """"ABSTRACT ""; ""ABBREVIATIONS ""; ""1. INTRODUCTION""; ""2. ANATOMIC ORGANIZATION OF THE BASAL GANGLIA ""; ""2.1. General Organization ""; ""2.2. Input and Output of Striatum and SNpc Connections ""; ""2.3. Input and Output of GP and SNpr, and STN Connections ""; ""2.4. Summary ""; ""3. PHYSIOLOGICAL FINDINGS OF THE BASAL GANGLIA IN ANIMALS ""; ""3.1. Neuronal Activity in Striatum, GPe and GPi ""; ""3.2. Neuronal Activity in STN, SNpc and SNpr "" |
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""3.3. Sequential Motor Actions and the Basal Ganglia""""3.4. Summary ""; ""4. CLINICAL SYMPTOMS OF PARKINSON�S DISEASE ""; ""4.1. Slowness of Movement and Abnormal Movement Sequence ""; ""4.2. Impaired Synergy of Movement/Posture and Freezing, Loss of Postural Reflex and Festination""; ""4.3. Prolongation of Reaction Time ""; ""4.4. Reorganized Voluntary Eye Hand Coordinated Movement""; ""4.5. Impaired Time Perception and Reproduction ""; ""4.6. Summary ""; ""5. FUNCTIONAL CONSIDERATIONS OF SPATIO-TEMPORAL PROCESSING FOR MOVEMENT SYNERGY IN THE BASAL GANGLIA AND PARKINSON�S DISEASE "" |
| Language |
English. |
| Subject |
Parkinson's disease.
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Symptomatic Parkinson's disease.
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Brain -- Diseases.
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Brain Diseases |
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Parkinson Disease |
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Parkinson Disease, Secondary |
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Maladie de Parkinson.
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Cerveau -- Maladies.
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HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
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MEDICAL -- Neurology.
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Symptomatic Parkinson's disease
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Brain -- Diseases
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Parkinson's disease
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| Added Author |
Yoshida, Chiyo.
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Ito, Ami.
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| Other Form: |
Print version: 9781619428300 161942830X (DLC) 2012470307 |
| ISBN |
1619428377 (electronic bk.) |
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9781619428379 (electronic bk.) |
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9781619428300 |
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161942830X |
| Standard No. |
DEBBG BV041049682 |
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DEBSZ 472771167 |
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