| Description |
1 online resource (1 page) : color illustrations. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
NREL/PO ; 5100-79587 |
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NREL/PO ; 5100-79587.
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| Note |
"Symposium on Biomaterials, Fuels and Chemicals, Society for Industrial Microbiology and Biotechnology, 4/26-28, 2021." |
| Funding |
DE-AC36-08GO28308. |
| Note |
Description based on online resource; title from PDF caption title (NREL, viewed Dec. 29, 2021). |
| Summary |
Combining separate unit operations into one where the best of each part can be maximized is one of the benefits of process intensification. An example is the combination of lignocellulosic biomass enzymatic hydrolysis with the downstream solid-liquid separation step to produce clarified sugars ready for fermentation or catalytic upgrading. The productivity and endpoint yield of enzymatic hydrolysis both enjoy the benefits of reduced feedback inhibition through the continuous removal of sugars by incorporating separations into the reactor. Likewise, the efficiency of recovering clarified sugars from the enzymatic hydrolysis slurry can be enhanced by operating separations equipment at steady-state conditions simultaneously with the continuously fed hydrolysis process. A key parameter that enables greater processing capacity while also raising the risks of failure is the solids loading or concentration. Higher solids loading allows for smaller reactor vessels and results in clarified sugars of higher concentration; however, required pumping power increases, reactor agitation may become ineffective, and membrane flux suffers. Feedstock material attributes influenced by upstream pretreatment must also be scrutinized more carefully: dilute-acid pretreated and deacetylated-and-disc-refined feedstocks exhibit different characteristics that affect agitation and pumping. The authors invite you to further explore the process science enabling the scale-up of this technology from conceptual work at the bench to pilot-scale industrially-relevant equipment where the challenges and solutions of integration and process optimization are expounded upon. |
| Subject |
Enzymes.
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Hydrolysis.
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Enzymes |
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Hydrolysis |
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Enzymes.
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Hydrolyse.
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enzyme.
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hydrolysis.
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Enzymes. (OCoLC)fst00913605
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Hydrolysis. (OCoLC)fst00965198
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| Indexed Term |
continuous enzymatic hydrolysis |
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membrane separations |
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process intensification |
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scale-up |
| Added Author |
Licheske, James J., author.
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McMillan, James Douglas, author.
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National Renewable Energy Laboratory (U.S.), issuing body.
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| Standard No. |
1818219 OSTI ID |
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0000-0002-7471-460X |
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0000-0003-2146-1300 |
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0000-0001-5143-9978 |
| Gpo Item No. |
0430-P-17 (online) |
| Sudoc No. |
E 9.28:NREL/PO-5100-79587 |
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