| Description |
1 online resource (ix, 234 pages) : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Cambridge Medicine |
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Cambridge medicine.
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| Bibliography |
Includes bibliographical references and index. |
| Summary |
"Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy - one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head - or the entire body - minimizes neuronal death, enabling the neonatal brain to be 'rescued' thus greatly improving developmental outcomes. Hypothermic neural rescue therapy has revolutionized the treatment of this condition and is a major recent achievement in neonatal medicine. This landmark book provides a brief scientific underpinning of hypothermic neural rescue therapy and lays out the evidence base for good practice. Internationally recognized authorities give practical advice, drawn from personal experience, on how to deliver hypothermia in the neonatal intensive care unit. A valuable addition to any neonatal unit, this is essential reading for neonatologists, neonatal nurses and paediatric neurologists."--Provided by publisher |
| Contents |
Scientific background -- Neurological outcome after perinatal asphyxia at term -- Molecular mechanisms of neonatal brain injury and neural rescue -- The discovery of hypothermic neural rescue therapy for perinatal hypoxic-ischaemic encephalopathy -- Clinical trials of hypothermic neural rescue -- Economic evaluation of hypothermic neural rescue -- Clinical neural rescue -- Challenges for parents and clinicians discussing neuroprotective treatments -- The pharmacology of hypothermia -- Selection of infants for hypothermic neural rescue -- Hypothermia during patient transport -- Whole body cooling for therapeutic hypothermia -- Selective head cooling -- Hypothermic neural rescue for neonatal encephalopathy in mid- and low-resource settings -- Cerebral function monitoring and EEG -- Magnetic resonance imaging in hypoxic-ischaemic encephalopathy and the effects of hypothermia -- Novel uses of hypothermia -- Neurological follow-up of infants treated with hypothermia -- Registry surveillance after neuroprotective treatment -- The future -- Novel neuroprotective therapies -- Combining hypothermia with other therapies for neonatal neuroprotection -- Biomarkers for studies of neuroprotection in infants with hypoxic ischaemic encephalopathy. |
| Subject |
Brain damage -- Patients -- Rehabilitation.
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Asphyxia neonatorum -- Treatment.
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Hypothermia, Induced.
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Newborn infants.
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Brain Injuries -- therapy |
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Asphyxia Neonatorum -- therapy |
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Hypothermia, Induced |
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Infant, Newborn |
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Mort apparente du nouveau-né -- Traitement.
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Hypothermie provoquée.
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Nouveau-nés.
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MEDICAL -- Surgery -- Neurosurgery.
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Brain damage -- Patients -- Rehabilitation
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Hypothermia, Induced
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Newborn infants
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| Added Author |
Edwards, David, 1952-
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Azzopardi, Denis V.
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Gunn, Alistair J.
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| Other Form: |
Print version: Neonatal neural rescue. Cambridge : Cambridge University Press, 2013 9781107681606 (DLC) 2012031827 (OCoLC)805892400 |
| ISBN |
9781107336940 (electronic bk.) |
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1107336945 (electronic bk.) |
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9781139565059 (electronic bk.) |
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1139565052 (electronic bk.) |
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9781107333628 (electronic bk.) |
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1107333628 (electronic bk.) |
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9781107681606 |
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110768160X |
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9781107335288 |
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1107335280 |
| Standard No. |
AU@ 000058388947 |
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DEBBG BV041049622 |
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NZ1 15028116 |
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