| Description |
1 online resource : illustrations (some color) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Note |
Online resource; title from PDF title page (EBSCO, viewed October 25, 2018). |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Front Cover; Current Trends and Future Developments on (Bio- ) Membranes: Membrane processes in the pharmaceutical and biotechnological field; Copyright; Contents; Contributors; Preface; Chapter 1: Ultra- and Microfiltration in Dairy Technology; 1. Introduction; 2. Applications of Ultrafiltration in Cascade Mode With Other Membrane Technologies; 2.1. UF Associated With MF; 2.2. UF Associated With NF/RO; 3. Protein Fractionation by Microfiltration; 4. ESL Milk Technology; 5. Ultrafiltration and Microfiltration in Diafiltration Mode; 6. Conclusion and Future Trends; References; Further Reading. |
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Chapter 2: Microfiltration in Pharmaceutics and Biotechnology1. Introduction; 2. Applications; 2.1. Cell Retention and Recycle; 2.2. Cell Harvesting and Broth Clarification; 2.3. Primary Separation of Product; 2.4. Microbe Removal; 3. Microfiltration Technologies; 3.1. Membranes and Modules; 3.2. Deadend Filtration; 3.3. Crossflow Filtration; 3.4. Monitoring and Control of Membrane Fouling; 4. Recent Advances; 4.1. Continuous Processing; 4.2. Alternating Tangential-Flow Filtration; 4.3. Single-Use Technologies; 5. Conclusions and Future Trends; Acknowledgments; References. |
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Chapter 3: Virus Removal and Virus Purification1. Introduction; 2. Virus Retentive Membranes for Virus Clearance; 2.1. Techniques to Characterize Virus Filtration Membranes; 2.2. Visualization Virus Retention within the Membrane; 2.3. Model Viruses and Surrogates; 2.4. Mechanistic Studies; 3. Membrane Adsorbers for Virus Clearance; 3.1. Virus Clearance with Membrane Adsorbers; 3.2. Anion Exchange (AEX) Membrane Adsorbers-Flow through Mode; 3.3. Cation Exchange (CEX) Membrane Adsorbers-Bind and Elute Mode; 3.4. Virus Purification with Membrane Adsorbers. |
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3.5. Virus Purification by Bind and Elute Mode3.6. Flow through Mode for Virus Purification; 4. Tangential Flow Filtration for Virus Purification; 5. Conclusion and Future Trends; Acknowledgments; References; Chapter 4: Nanofiltration in the Pharmaceutical and Biopharmaceutical Technology; 1. Introduction; 2. Multistage Membrane Processes with Potential to Broaden Applications in Industry; 3. Membrane Cascades Operating in Batch Diafiltration Mode; 4. Membrane Cascades Operating in Continuous Mode; 5. Conclusions and Future Trends; References. |
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Chapter 5: Purification of New Biologicals Using Membrane-Based Processes1. Important Classes of Biologicals; 1.1. Antimicrobial Peptides; 1.2. Toxins; 1.3. Advanced Therapy Medicinal Products; 1.3.1. Virus-Based Products; 1.3.2. Cell-Based Products; 2. Membrane-Based Separation and Purification of Biologicals-Status, Trends, and Future Developments; 2.1. Perfusion for the Intensified Production of Biologicals in Animal Cells; 2.2. AMP Purification Based on Inclusion Bodies; 2.3. Toxin Purification and Concentration; 2.4. Clarification and Purification of Virus-Based Products. |
| Summary |
Current Trends and Future Developments on (Bio- ) Membranes: Membrane Processes in the Pharmaceutical and Biotechnological field presents the main membrane techniques along with their basic principles, mode of operations, and applications. It covers well-known techniques such as ultrafiltration and membrane chromatography, while also exploring emerging membrane technologies which are finding their way in pharmaceutical and biotechnology industries, including membrane emulsification, membrane bioreactors, and solvent-resistant nanofiltration. State-of-the-art applications of membrane systems in areas such as drug delivery and virus removal are also investigated by leading experts in the field. Current Trends and Future Developments on (Bio- ) Membranes: Membrane Processes in the Pharmaceutical and Biotechnological field is a definitive reference for academics, post-graduates, and researchers in the subjects of biochemical engineering, pharmaceutics, and biotechnology. It is also useful to R & D companies and institutions in these areas, specifically those interested in bioseparations, biopurification, bioproduction, and drug delivery. |
| Subject |
Membranes (Biology)
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Membranes |
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Membranes (Biologie)
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SCIENCE -- Life Sciences -- Anatomy & Physiology.
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Membranes (Biology)
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| Added Author |
Basile, Angelo (Angelo Bruno), editor.
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Charcosset, Catherine, editor.
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| Added Title |
Membrane processes in the pharmaceutical and biotechnological field |
| Other Form: |
Print version: 9780128136065 |
| ISBN |
9780128136072 (electronic bk.) |
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0128136073 (electronic bk.) |
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9780128136065 |
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0128136065 |
| Standard No. |
AU@ 000065026019 |
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UKMGB 019087017 |
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