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Author Agarwal, Shikha, author.

Title Imidazole-based drug discovery / Shikha Agarwal.

Publication Info. Amsterdam, Netherlands ; Oxford, United Kingdom ; Cambridge, MA, United States : Elsevier, [2022]
©2022

Copies

Location Call No. OPAC Message Status
 Axe Elsevier ScienceDirect Ebook  Electronic Book    ---  Available
Description 1 online resource (xix, 351 pages) : illustrations.
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Heterocyclic drug discovery series
Heterocyclic drug discovery.
Bibliography Includes bibliographical references and index.
Contents 2.3.5 Using benzil, aldehyde, and ammonium acetate -- 2.4 Tetra-substituted imidazole derivatives -- 2.4.1 Using aminoethylpiperazine -- 2.4.2 Using prop-2-ynylamine -- 2.4.3 Using benzil, aldehydes, ammonium acetate, and aniline -- 3 Imidazole hybrids -- 3.1 Imidazole fused heterocycles -- 3.2 Benzimidazole fused heterocycles -- 4 Benzimidazole -- 4.1 Hoebrecker synthesis -- 4.2 Synthesis of benzimidazoles using o -phenylenediamine and acids -- 4.3 Synthesis of benzimidazoles using o -phenylenediamine and acid anhydride -- 4.4 Synthesis of benzimidazoles using o -phenylenediamine and alcohols
4.5 Synthesis of benzimidazoles using o -phenylenediamine and alkyl halides -- 4.6 Synthesis of benzimidazoles using ketones -- 4.7 Synthesis of benzimidazoles using o -phenylenediamine and aldehydes -- 5 Conclusion -- Conflict of interest -- Acknowledgments -- Funding source -- References -- Chapter 2 Biological profile of imidazole-based compounds as anticancer agents -- 1 Introduction -- 2 Imidazole-based heterocycles -- 2.1 Imidazole as the main nucleus in the anticancer compounds -- 2.1.1 Mono-substituted imidazole derivatives -- 2.1.2 Disubstituted imidazole derivatives
2.1.3 Trisubstituted imidazole derivatives -- 2.1.4 Tetra-substituted imidazole derivatives -- 2.2 Imidazole hybrids as anticancer agents -- 2.3 Imidazole fused heterocycles -- 2.3.1 Imidazole fused heterocycles -- 2.3.2 Benzimidazole fused heterocycles -- 2.4 Imidazole-based metal complexes as anticancer agents -- 3 Conclusion and future challenges -- Conflict of interest -- Acknowledgment -- Funding source -- References -- Chapter 3 Recent advancements on imidazole containing heterocycles as antitubercular agents -- 1 Introduction -- 2 Imidazole-based heterocycles -- 2.1 Substituted imidazoles
2.2 Hybrid Imidazoles -- 2.3 Fused imidazoles -- 2.4 Linker imidazole -- 2.5 Benzimidazole -- 3 Conclusion -- Conflict of interest -- Acknowledgments -- Funding source -- References -- Chapter 4 Imidazole derivatives: Impact and prospects in antiviral drug discovery -- 1 Introduction -- 2 Imidazole derivatives and their action against different viruses -- 2.1 Zika virus -- 2.2 Influenza -- 2.3 SARS-COVID -- 2.4 Dengue -- 2.5 Hepatitis -- 2.6 HIV -- 2.7 Miscellaneous -- 3 Conclusion -- Acknowledgments -- Conflict of interest -- Funding source -- References
Note Chapter 5 Imidazole heterocycles: Therapeutically potent lead compounds as antimicrobials.
Online resource; title from PDF title page (ScienceDirect platform, viewed April 19, 2022).
Subject Imidazoles.
Drugs.
Drug development.
Imidazoles
Pharmaceutical Preparations
Imidazole.
Médicaments.
Médicaments -- Développement.
Drug development
Drugs
Imidazoles
Other Form: Print version: 0323854796 (OCoLC)1257403690
ISBN 9780323903639
0323903630
9780323854795
Standard No. AU@ 000070668214
AU@ 000073114593

 
    
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