| Description |
1 online resource (xi, 413 pages) : illustrations. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Annual reports in medicinal chemistry ; v. 31
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| Bibliography |
Includes bibliographical references and indexes. |
| Note |
Print version record. |
| Summary |
Advances in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. |
| Contents |
Front Cover; ANNUAL REPORTS IN MEDICINAL CHEMISTRY, Volume 31; Copyright Page; CONTENTS; CONTRIBUTORS; PREFACE; SECTION I: CENTRAL NERVOUS SYSTEM DISEASES; Chapter 1. Neuropeptide Y: At the Dawn of Subtype Selective Antagonists; Chapter 2. Gonadal Steroid Receptors: Possible Roles in the Etiology and Therapy of Cognitive and Neurological Disorders; Chapter 3. P2 Purinoceptors: A Family of Novel Therapeutic Targets; Chapter 4. The Metabotropic Glutamate Receptors; Chapter 5. Drugs in Anesthetic Practice; SECTION II: CARDIOVASCULAR AND PULMONARY DISEASES |
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Chapter 6. Thrombin and Factor Xa InhibitionChapter 7. Inhibitors of Types I and V Phosphodiesterase: Elevation of cGMP as a Therapeutic Strategy; Chapter 8. Chronic Pulmonary Inflammation and Other Therapeutic Applications of PDE IV Inhibitors; Chapter 9. Endothelin Antagonists; Chapter 10. GPllb/llla Antagonists; Chapter 11. Atherothrombogenesis; Chapter 12. Neurokinin Receptor Antagonists; SECTION III: CANCER AND INFECTIOUS DISEASES; Chapter 13. Antibacterial Agents; Chapter 14. Semisynthetic Glycopeptide Antibiotics; Chapter 15. Chemotherapy of Malaria |
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Chapter 16. Recent Advances in Tyrosine Kinase InhibitorsChapter 17. Recent Advances in the Chemistry and Biology of Antimycobacterial Agents; Chapter 18. Ras Farnesyltransferase Inhibitors; SECTION IV: IMMUNOLOGY, ENDOCRINOLOGY, AND METABOLIC DISEASES; Chapter 19. Estrogen Receptor Modulators: Effects in Non-Traditional Target Tissues; Chapter 20. Cell Adhesion lntegrins as Pharmaceutical Targets; Chapter 21. Treating Obesity in the 21st Century; Chapter 22. Anti-Osteoporosis Agents; Chapter 23. Nitric Oxide Synthase Inhibitors; Chapter 24. Inhibition of Matrix Metalloproteinases |
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SECTION V: TOPICS IN BIOLOGYChapter 25. Cell Cycle Control and Cancer; Chapter 26. Regulation of Apoptosis by Members of the ICE Family and the Bcl2 Family; Chapter 27. The Role of JAKs and STATs in Transcriptional Regulation by Cytokines; Chapter 28. Novel Inhibitors of the Proteasome and Their Therapeutic Use in Inflammation; Chapter 29. The MAP Kinase Family: New ""MAPs"" for Signal Transduction Pathways and Novel Targets for Drug Discovery; SECTION VI: TOPICS IN DRUG DESIGN AND DISCOVERY; Chapter 30. New NMR Methods for Structural Studies of Proteins to Aid in Drug Design |
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Chapter 31. Solid-Phase Synthesis: Applications to Combinatorial LibrariesChapter 32. Application of Mass Spectrometry for Characterizing and Identifying Ligands from Combinatorial Libraries; Chapter 33. Plasma Protein Binding of Drugs; SECTION VII: TRENDS AND PERSPECTIVES; Chapter 34. To Market, To Market -- 1995; Chapter 35. The Protein Structure Project, 1950-1959: First Concerted Effort of a Protein Structure Determination in the U.S.; COMPOUND NAME, CODE NUMBER AND SUBJECT INDEX, VOLUME 31; CUMULATIVE CHAPTER TITLES KEYWORD INDEX, VOLUMES 1-31; CUMULATIVE NCE INTRODUCTION INDEX, 1983-1995 |
| Language |
English. |
| Subject |
Pharmaceutical chemistry -- Periodicals.
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Clinical chemistry -- Periodicals.
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Chimie pharmaceutique -- Périodiques.
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Chimie clinique -- Périodiques.
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MEDICAL -- Drug Guides.
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MEDICAL -- Pharmacology.
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MEDICAL -- Pharmacy.
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MEDICAL -- Nursing -- Pharmacology.
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Clinical chemistry
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Pharmaceutical chemistry
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| Genre/Form |
Periodical |
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periodicals.
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Periodicals
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Periodicals.
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Périodiques.
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| Added Author |
Bristol, James A., 1946-
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American Chemical Society. Division of Medicinal Chemistry.
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| Other Form: |
Print version: Annual reports in medicinal chemistry. Volume 31. San Diego : Academic Press, ©1996 0120405318 9780120405312 (OCoLC)41209980 |
| ISBN |
9780080583754 (electronic bk.) |
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008058375X (electronic bk.) |
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0120405318 (electronic bk.) |
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9780120405312 (electronic bk.) |
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1281739928 |
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9781281739926 |
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9786611739928 |
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6611739920 |
| Standard No. |
CHBIS 010355987 |
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CHVBK 329771450 |
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DEBSZ 405329717 |
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DEBSZ 482460814 |
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AU@ 000056664600 |
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