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Title Biointegration of medical implant materials : science and design / edited by Chandra P. Sharma.

Imprint Boca Raton : CRC Press ; Oxford : Woodhead, 2010.

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Location Call No. OPAC Message Status
 Axe Elsevier ScienceDirect Ebook  Electronic Book    ---  Available
Description 1 online resource (xv, 412 pages) : illustrations.
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Woodhead publishing in materials
Woodhead Publishing in materials.
Bibliography Includes bibliographical references and index.
Note Print version record.
Summary Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integrationDiscusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstructionReviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery.
Contents Cover; Biointegration of medical implant materials: Science and design; Copyright; Contents; Contributor contact details; Preface; 1 Biointegration: an introduction; 1.1 Introduction; 1.2 Biointegration of biomaterials for orthopedics; 1.3 Biointegration of biomaterials for dental applications; 1.4 AlphaCor artificial corneal experience; 1.5 Biointegration and functionality of tissue engineering devices; 1.6 Percutaneous devices; 1.7 Future trends; 1.8 References; Part I Soft tissue biointegration; 2 Biocompatibility of engineered soft tissue created by stem cells; 2.1 Introduction.
2.2 Bone: from tissue to molecular organization2.3 Bone development; 2.4 Bone homeostasis; 2.5 Bone repair after injury; 2.6 Bone and joint disease; 2.7 Current treatment options and total joint replacements; 2.8 Current challenges of titanium implants; 2.9 Current titanium modifications for improved integration; 2.10 Mimicking nature toward achieving titanium 'biointegration': cytokines and implants; 2.11 Growth factor delivery: why is controlled and sustained release important?; 2.12 Future trends; 2.13 Acknowledgements; 2.14 Sources of further information and advice; 2.15 References.
3 Replacement materials for facial reconstruction at the soft tissue- bone interface3.1 Introduction; 3.2 Facial reconstruction; 3.3 Materials used in traditional interfacial repair; 3.4 Surface modification of facial membranes for optimal biointegration; 3.5 Future trends; 3.6 Acknowledgements; 3.7 References; 4 Corneal tissue engineering; 4.1 Introduction; 4.2 Characteristics of the human cornea and its regeneration; 4.3 Special conditions for wound healing and tissue regeneration of the cornea; 4.4 Approaches to corneal tissue engineering; 4.5 Future trends; 4.6 References.
5 Tissue engineering for small-diameter vascular grafts5.1 Introduction; 5.2 Required characteristics of tissue engineered blood vessels; 5.3 Approaches to vascular tissue engineering; 5.4 Future trends; 5.5 Conclusion; 5.6 References; 6 Stem cells for organ regeneration; 6.1 Introduction; 6.2 Basic components of tissue engineering; 6.3 Tissue engineering and stem cells in organ regeneration; 6.4 Conclusions; 6.5 References; Part II Drug delivery; 7 Materials facilitating protein drug delivery and vascularisation; 7.1 Introduction; 7.2 Hydrogel classification.
7.3 Factors influencing protein encapsulation and release7.4 Tissue engineering applications: vascularisation and protein delivery; 7.5 Conclusions; 7.6 Acknowledgements; 7.7 References; 8 Inorganic nanoparticles for targeted drug delivery; 8.1 Introduction; 8.2 Calcium phosphate nanoparticles; 8.3 Gold nanoparticles; 8.4 Iron oxide nanoparticles; 8.5 Conclusion; 8.6 Acknowledgements; 8.7 References; 9 Alginate-based drug delivery devices; 9.1 Introduction; 9.2 Alginate biopolymers; 9.3 Drug delivery using alginate matrices; 9.4 Future trends; 9.5 Acknowledgement; 9.6 References.
Subject Implants, Artificial.
Implants, Artificial -- Design and construction.
Biomedical materials -- Design.
Tissue engineering.
Biomedical materials.
Biocompatible Materials
Biomedical and Dental Materials
Drug Delivery Systems
Prostheses and Implants
Tissue Engineering
Prothèses internes.
Génie tissulaire.
Biomatériaux.
HEALTH & FITNESS -- Holism.
HEALTH & FITNESS -- Reference.
MEDICAL -- Alternative Medicine.
MEDICAL -- Atlases.
MEDICAL -- Essays.
MEDICAL -- Family & General Practice.
MEDICAL -- Holistic Medicine.
MEDICAL -- Osteopathy.
Biomedical materials
Implants, Artificial
Tissue engineering
Added Author Sharma, Chandra P.
Other Form: Print version: Biointegration of medical implant materials. Boca Raton : CRC Press ; Oxford : Woodhead, 2010 9781845695095 1845695097
ISBN 1845699807 (electronic bk.)
9781845699802 (electronic bk.)
9781845695095 (hbk. ; Woodhead Pub.)
1845695097 (hbk. ; Woodhead Pub.)
9781439830642 (hbk. ; CRC Press)
1439830649 (hbk. ; CRC Press)
Standard No. AU@ 000061137864
DEBBG BV042316701
DEBSZ 414265963
AU@ 000055872989

 
    
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