| Edition |
1st ed. |
| Description |
1 online resource : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
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data file rda |
| Bibliography |
Includes bibliographical references. |
| Summary |
Annotation Increased caloric intake, increased refined carbohydrate consumption, and physical inactivity have led to an explosion in the worldwide incidence of abdominal obesity and the emerging epidemic of insulin resistance, resulting in an increase of metabolic syndrome. Physicians can use the metabolic syndrome concept to guide focused lifestyle changes, lower blood pressure goals, and earlier intervention with aspirin, LDL-lowering drugs, and perhaps insulin-sensitizing medications. The comprehensive ABCDE approach presented in this book provides a memory tool for use in everyday clinical practice. In this unique, easy-to-read text, the 17 most important clinical trials in the field of the metabolic syndrome are presented, that every clinician should know. |
| Note |
Print version record. |
| Contents |
Intro -- Title page -- Colophon -- Table of Contents -- Introduction -- The Metabolic Syndrome. A Global Problem -- Introduction -- A Global Problem -- What is the Metabolic Syndrome? -- Why is the Metabolic Syndrome Concept Useful? -- Misunderstandings about Use of Metabolic Syndrome -- Why is the Metabolic Syndrome so Interesting? -- References -- Defining the Metabolic Syndrome -- Early History of the Metabolic Syndrome -- Pathophysiology vs. Predictive Value -- Criticisms of the Metabolic Syndrome -- The "Harmonized" Definition of Metabolic Syndrome -- References -- Causes and Components of the Metabolic Syndrome -- Genetics of the Metabolic Syndrome -- Abdominal Obesity -- Insulin Resistance -- Atherogenic Dyslipidemia -- Essential Hypertension -- Glucose Intolerance -- Subclinical Inflammation -- Fatty Liver Disease -- Obstructive Sleep Apnea -- References -- Consequences of the Metabolic Syndrome -- Cardiovascular Disease -- Type 2 Diabetes -- Microalbuminuria and Chronic Kidney Disease -- Sexual Dysfunction (Men and Women) -- Cognitive Decline -- Cancer -- References -- The Comprehensive "ABCDE" Approach to Management -- Rationale for a Comprehensive Approach -- The ABCDE approach -- References -- Assessment of Cardiovascular Risk -- Traditional Risk Models -- Lifetime Risk -- Metabolic Syndrome and Unaccounted Risk -- Emerging Cardiometabolic Risk Factors -- Reclassification with the Metabolic Syndrome -- Novel Risk Detection Strategies -- References -- Aspirin and Antithrombotics -- Mechanisms of Increased Thrombosis in the Metabolic Syndrome -- Brief Overview of Platelet Function -- Therapies With Available Evidence -- Possible Aspirin Resistance in the Metabolic Syndrome -- Other Therapies -- Treatment recommendations -- References -- Blood Pressure -- Hypertension -- Definition. |
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Mechanisms of Increased Blood Pressure in the Metabolic Syndrome -- Lifestyle Therapy -- Pharmacologic Agents: The Renin-Angiotensin-Aldosterone Axis -- Thiazide Diuretics -- Beta-Blockers -- Calcium Channel Blockers -- Metabolic Considerations. Progression to Diabetes -- Blood Pressure Target -- Guidelines and Recommendations -- References -- Cholesterol -- Atherogenic Dyslipidemia -- Mechanisms of Atherogenic Dyslipidemia -- Measurement -- Therapies with Available Evidence -- Guidelines and Recommendations -- References -- Diet and Weight Management -- Weight Loss -- The Mediterranean Diet -- The Low Glycemic Index Approach -- Sugar Sweetened Beverages -- The Benefit of Nuts -- Pharmacologic and Surgical Therapy for Obesity -- Refer to a Nutritionist? -- References -- Diabetes Prevention -- Progression to Type 2 Diabetes -- Clinical Trial Evidence -- Gaps in the Evidence -- Guidelines -- References -- Exercise Therapy -- Fitness -- Mechanisms of Harm from Sedentary Lifestyle: Decreased Fitness -- Mechanisms of Harm from Sedentary Lifestyle: Increased Fatness -- Exercise: A Selective Therapy for Metabolic Syndrome? -- Guideline Recommendations -- References -- Metabolic Syndrome in the Pediatric Population -- The Unique Challenge of Pediatric Metabolic Syndrome -- Defining Pediatric Metabolic Syndrome -- Scientific Statement from the American Heart Association -- Population-Based Treatment Strategies Targeted at Youth -- References -- Summary of Treatment Approaches -- Appendix. Clinical trials -- Finnish Diabetes Prevention Study -- Diabetes Prevention Program (DPP) -- JPAD Trial -- POPADAD Trial -- ACCORD Blood Pressure Trial -- JUPITER trial -- VA-HIT trial -- ACCORD Lipid trial -- AIM-HIGH trial -- JELIS trial -- Lyon Heart Study -- Esposito Mediterranean Diet Trial -- DREAM Trial -- ACT-NOW Trial -- CANOE trial -- Tjønna Exercise Trial. |
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CPAP for the Metabolic Syndrome -- References -- Authors. |
| Subject |
Metabolic syndrome.
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Diabetes.
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Metabolic Syndrome. |
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Syndrome métabolique.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Diabetes
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Metabolic syndrome
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| Added Author |
Tota-Maharaj, Rajesh.
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| Other Form: |
Print version: Blaha, Michael J. Metabolic syndrome. 1st ed. Torino : SEEd, ©2012 9788897419198 |
| ISBN |
9788897419204 (electronic bk.) |
|
8897419208 (electronic bk.) |
|
8897419194 |
|
9788897419198 |
|
9788897419198 |
|
9788897419204 |
| Standard No. |
AU@ 000053024104 |
|
DEBBG BV040884253 |
|
DEBBG BV043786757 |
|
DEBBG BV044188531 |
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DEBSZ 472759132 |
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NZ1 15024397 |
|
