Third edition / Richard B. Silverman, Mark W. Holladay.
Description
1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Bibliography
Includes bibliographical references and index.
Contents
Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.
Note
Print version record.
Summary
The Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.
