| Description |
1 online resource. |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Genetics-Research and issues |
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Genetics--research and issues series.
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| Bibliography |
Includes bibliographical references and index. |
| Note |
Description based on print version record. |
| Contents |
NEUROFIBROMATOSIS TYPE 1 ; Library of Congress Cataloging-in-Publication Data; Contents ; Acknowledgment ; Introduction ; Chapter I Molecular Pathogenesis of Neurofibromatosis Type 1 ; Abstract ; Introduction ; Epidemiology of NF1 ; Clinical Features of NF1 ; Skin Manifestations ; Skeletal and Osseous Abnormalities ; Vascular Lesions ; Psychiatric Disorders and Cognitive Dysfunction; Rare Manifestations ; RASopathies ; Dysplasia and Developmental Defects ; Molecular Genetics of NF1 ; Genetic Diagnosis ; Tumors Associated with NF1 ; Disease Modifier Genes in NF1. |
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Molecular Pathogenesis of NF1Using Systems Approaches to Study NF1 ; Current Treatment and Disease Management ; Conclusion ; References ; Chapter II Imaging of Plexiform Neurofibromas in Neurofibromatosis Type 1 ; Abstract ; Introduction ; Imaging Appearance of Plexiform Neurofibromas ; Plexiform Neurofibroma Types ; Volumetric Analysis ; Cranial Nerves ; Spinal Nerves ; Neck, Mediastinum, Chest ; Abdomen, Pelvis ; Malignant Peripheral Nerve Sheath Tumors (MPNSTs) ; Conclusion ; References ; Chapter III Surgical Treatment of GiantNeurofibromas ; Abstract ; Introduction. |
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Surgical Techniques Discussion ; Conclusion ; References ; Chapter IV Neurofibromatosis Type 1-Associated Nervous System Tumors and Current Treatment Strategies ; Abstract ; Introduction ; Central Nervous System Tumors in Children with NF1 ; Low Grade Glioma: Clinical Presentation ; Low Grade Glioma: Imaging Characteristics ; Low Grade Glioma: Prognosis ; Low Grade Glioma: Treatment Modalities ; 1. Role of Surgery ; 2. Radiation Therapy ; 3. Chemotherapy; 4. Targeted Therapy ; RAS-MAPK Pathway; Peripheral Nervous System Tumors in Children with NF1. |
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Plexiform Neurofibromas: Clinical Presentation Plexiform Neurofibromas: Imaging Characteristics ; Plexiform Neurofibromas: Prognosis ; Plexiform Neurofibromas: Treatment Modalities ; 1. Role of Surgery ; 2. Radiation Therapy ; 3. Chemotherapy ; 4. Targeted Therapy ; a) mTOR Pathway ; Interferon Treatment ; b) Anti-angiogenic Treatment ; c) Tyrosine Kinase Inhibitor Treatment ; Malignant Peripheral Nerve Sheath Tumor (MPNST): Clinical Presentation ; MPNST: Imaging Characteristics ; MPNST: Prognosis ; MPNST: Treatment Modalities ; 1. Role of Surgery ; 2. Radiation Therapy ; 3. Chemotherapy. |
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4. Targeted Therapy a) Tyrosine Kinase Inhibitor Treatment; b) Angiogenic Pathways ; c) Cytoskeletal Remodeling ; Conclusion ; References ; Chapter V Outcome Measures for Optic Pathway Gliomas ; Abstract ; Introduction ; Epidemiology of OPGs ; Presentation of OPGs ; Clinical Symptoms ; Diagnostic Imaging ; Pathology ; Management of OPGs ; Clinical Course ; Surveillance ; Treatment ; Outcome Measures ; Anatomical Outcomes (MRI) ; Visual Outcomes ; Alternative Outcome Measures ; Diffusion and Perfusion Imaging; Diffusion Tensor Imaging ; Positron Emission Tomography. |
| Subject |
Neurofibromatosis.
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Neurofibromatosis in children.
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Neurofibromatoses |
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Neurofibromatose.
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Neurofibromatose chez l'enfant.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Neurofibromatosis
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Neurofibromatosis in children
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| Added Author |
Karajannis, Matthias A., editor.
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Allen, Jeffrey, editor.
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| Other Form: |
Print version: Neurofibromatosis type 1 New York : Nova Biomedical, [2013] 9781628081596 (hbk.) (DLC) 2013940382 |
| ISBN |
9781628081657 pdf |
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1628081651 |
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1628081597 hbk. |
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9781628081596 hbk. |
| Standard No. |
DEBBG BV041572594 |
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AU@ 000062327261 |
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