1. Introduction -- 2. Methods -- 3. Results -- 4. Discussion and conclusions -- Appendix A: Search strategy -- Appendix B: Evidence table of included studies -- Appendix C: Excluded full-text articles -- Appendix D: Depression scale standard cut-points -- Appendix E: Funnel plots for comparisons with publication bias.
Summary
RAND researchers conducted a systematic review that synthesized evidence from randomized controlled trials of omega-3 fatty acids--used adjunctively or as monotherapy--to provide estimates of their efficacy and safety in treating adults with major depressive disorder.
