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Title Thalassemia : causes, treatment options and long-term health outcomes / Makenzie Greene, editor.

Publication Info. New York : Nova Biomedical, 2014.


Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource (282 pages) : illustrations, tables
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Recent Advances in Hematology Research
Recent advances in hematology research series.
Bibliography Includes bibliographical references and index at the end of each chapters.
Note Print version record.
Contents THALASSEMIA: CAUSES, TREATMENT OPTIONS AND LONG-TERM HEALTH OUTCOMES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Cure of Thalassemia Major Using Related and Unrelated Donor Cord Blood Stem Cell Transplantation; Abstract; Introduction; Related Donor Cord Blood Transplantation for Thalassemia; Unrelated Donor Cord Blood Transplantation for Thalassemia; Discussion; References; Chapter 2: The Differential Diagnosis of Microcytosis; Abstract; 1. Disease Characteristics; 2. Clinical Description.
3. From Genotype to Phenotype: Clinical Diversity of b Thalassemia4. Pathophysiology of Thalassemia; 5. Microcytic Anemia in the Laboratory; References; Chapter 3: Computer Aided Diagnosis of Thalassaemias: An Overview; Abstract; Introduction; Computer Aided Diagnosis; Related Works; Main Results; Conclusion; References; Chapter 4: Hematopietic Stem Cell Transplantation for Thalassemia, Price and Prejudice; Abstract; Introduction; Long-term Supportive Care vs. Definitive Cure by BMT; Sources of Transplantable Stem Cells; BMT Preparative Regimens; The Issue of Splenectomy Prior to BMT.
Hepatitis C and BMTCosts and Sustainability; BMT and Gene Therapy; Prospects; Conclusion; References; Chapter 5: Screening and Genotyping of Beta Thalassemia; Abstract; Definition, Epidemiology and Etiology; Diagnosis of Beta Thalassemia; Screening of <U+0042>eta Thalassemia Trait; Genetic Diagnosis -- DNA Analysis; Conclusion; References; Chapter 6: Molecular Therapies for Treatment of Thalassemia; Abstract; Introduction; Gene Therapy by Addition of Globin Genes via Retroviral Vectors; Gene Editing for Treatment of Thalassemia; Induced Pluripotent Stem Cells.
The Current Gene Therapy Clinical Trials for ThalassemiaConclusion; References; Chapter 7: Developments in the Molecular Diagnosis of Beta-Thalassaemia; Abstract; Introduction; Common Molecular Diagnostic Methods for Genetic Screening of Beta-thalassaemia Mutations; Noninvasive Prenatal Testing for Beta-thalassaemia; Conclusion; References; Chapter 8: Antioxidant Therapies for Thalassemia; Abstract; 1. Introduction; 2. Oxidative Stress in Thalassemia; 3. Antioxidant Defenses; 4. Dietary Antioxidants in Thalassemia; 5. Pharmaceutical Antioxidants in Thalassemia.
6. Future Research of Antioxidants in ThalassemiaConclusion; References; Chapter 9: Calcifications in Thalassemia: An Important Complication; Abstract; Introduction; How Can Calcification Occurs in Thalassemic Patients?; Abnormal Calcification in Internal Organs in Thalassemic Patients; Conclusion; References; Chapter 10: Multi-Target Therapeutic Modalities for b-Hemoglobinopathies; Abstract; Quantitative and Qualitative Abnormalities of HbA and Their Amelioration by HbF; Oxidative Stress; Iron-Overload (IO); Hemin; Erythropoietin; Dietary Products As Iron-Chelating and Anti-Oxidant Agents.
Subject Thalassemia.
Thalassemia -- Treatment.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Thalassemia. (OCoLC)fst01149118
Genre/Form Electronic books.
Added Author Greene, Makenzie, editor.
Other Form: Print version: Thalassemia : causes, treatment options and long-term health outcomes. New York : Nova Biomedical, 2014 xv, 264 pages Recent advances in hematology research series. 9781631179549
ISBN 9781631179556 (electronic bk.)
1631179551 (electronic bk.)
1631179543 (hardcover)
Standard No. AU@ 000053331055

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