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Title Current immunosuppressive therapy in organ transplantation / Huifang Chen and Shiguang Qian, editors.

Publication Info. New York : Nova Biomedical, [2015]

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Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Organ transplantation research horizons
Organ transplantation research horizons.
Bibliography Includes bibliographical references and index.
Note Print version record.
Contents CURRENT IMMUNOSUPPRESSIVE THERAPY IN ORGAN TRANSPLANTATION ; CURRENT IMMUNOSUPPRESSIVE THERAPY IN ORGAN TRANSPLANTATION 0; Contents ; Foreword ; Preface; Part I: Immunologic Basis ; Chapter 1 Immunology Principles in Organ Transplantation ; Abstract ; Abbreviations ; Introduction ; The "Anatomy" of the Immune System ; Mononuclear Phagocytes ; Neutrophils ; Natural Killer Cells ; Dendritic Cells ; B Cells ; T Cells ; Platelets ; Lymphoid Tissue ; Innate Immune System ; Complement ; Adaptive Immunity and Allograft Rejection ; Hyperacute Rejection (HAR); Acute Rejection
Acute Antibody Mediated Rejection (AMR) Chronic Rejection ; Human Leucocyte Antigens and Calculating Immunological Risk Prior to Solid Organ Transplantation ; Tolerance and Immune Regulation ; Tregs ; Myeloid Derived Suppressor Cells ; Mixed Chimerism -- A Spectrum from Tolerance to Graft versus Host Disease ; Infection, Malignancy and Monitoring Alloimmunity; Composite Tissue Transplantation; Xenotransplantation ; References ; Chapter 2 Cellular and Humoral Responses in Organ Transplantation; Abstract ; Abbreviations ; Introduction; T Cell Biology in Transplantation
Direct and Indirect Alloantigen Recognition TCR Signal Transduction ; Costimulatory and Inhibitory Signals ; Cytokine Regulation of T Cell Response ; T Cell Response to Allograft ; T Cell-Targeted Therapies for Transplantation ; Tolerance in Transplantation ; Memory T Cells in Transplantation ; B Cell Biology in Transplantation ; B Cells and Antibody Production ; Alloreactive Antibodies; Antibody-Mediated Rejection and Treatments ; Antigen-Presenting B Cells in Transplant Tolerance ; Conclusion ; References
Chapter 3 Historical Remarks of Immunosuppressive Therapy in Organ Transplantation Abstract ; Abbreviations ; Introduction; Azathioprine (1960s -- 1980s); Cyclophosphamide (1960s -- 1980s); Induction Therapies (1960s -- Present) ; Cyclosporine (1980s -- 1990s) ; Tacrolimus, Rapamycin and Mycophenolate Mofetil (1990s -- 2010s) ; Tacrolimus (FK506, Prograf) ; Sirolimus and Everolimus ; Mycophenolate Mofetil; Current Mainstay Immunosuppressants ; Replacement of CNIs and Application of Biological Agents (2010s -- Future) ; CNIs Nephrotoxicity; CNIs Replacement with MMF and Sirolimus
Application of Biological Agents Summary ; References; Chapter 4 Animal Models in Immunosuppression ; Abstract ; Abbreviations ; Introduction ; Rodent Models for Immunosuppression; Organ-Specific Rodent Transplant Models; Rodent Models of Rejection ; Large Animal Models ; Common Large Animal Models ; Costimulation Blockade ; Cell Depletion; Tolerance Strategies ; Studies of Toxicity: Cyclosporine as Paradigm ; References ; Chapter 5 Ethical Issues of Immunosuppressive Drugs Use in Organ Transplantation ; Abstract ; Abbreviations ; Introduction ; Basic Ethical Principles in ISD Treatment
Subject Transplantation immunology.
Immunosuppressive agents.
Transplantation Immunology
Immunosuppressive Agents
Greffe (Chirurgie) -- Immunologie.
Immunosuppresseurs.
MEDICAL -- Pharmacology.
Immunosuppressive agents
Transplantation immunology
Added Author Chen, Huifang (Professor of Surgery), editor.
Qian, Shiguang, editor.
Other Form: Print version: Current immunosuppressive therapy in organ transplantation. New York : Nova Biomedical, [2015] 9781634828987 (DLC) 2015939636
ISBN 9781634829472 (ebook)
1634829476
1634828984 (hbk.)
9781634828987 (hbk.)

 
    
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