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Author Kondo, Karli, author.

Title End-stage renal disease and depression : a systematic review / Karli Kondo [and four others].

Publication Info. Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Health Services Research & Development Service, 2020.

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Description 1 online resource (vi, 101 pages) : illustrations (some color).
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Evidence synthesis program
Evidence-based synthesis program (Series)
Note "January 2020."
Bibliography Includes bibliographical references (pages 75-80).
Funding VA ESP 05-225
Note Description based on online resource; title from PDF cover (VA, viewed February 19, 2021).
Summary AIM: We conducted a systematic review to evaluate the performance characteristics of screening tools for depression in Veterans with end-stage renal disease (ESRD), and to better understand the impact, benefits, and harms of depression screening and subsequent treatment for depression. METHODS: We searched electronic databases, clinical trial registries, and reference lists through April 2019 for diagnostic accuracy studies of depression tools for patients with ESRD and for trials examining the effectiveness of interventions for the treatment of depression in patients with ESRD. We abstracted data on study design, interventions, and outcomes. Dual assessment of a study's full text, quality, and strength of evidence (SOE) was agreed upon by consensus using pre-specified criteria. RESULTS: We included 20 treatment RCTs and 16 diagnostic accuracy studies. The best-studied tool was the Beck Depression Inventory-II (BDI-II). Across 4 BDI-II studies, a cutoff of ≥16 provides the best balance between sensitivity and specificity. The BDI-II performed reasonably well when compared to a gold standard clinical interview. SSRIs were the most studied type of drug and the evidence was largely insufficient. We found moderate SOE that long-term, high-dose Vitamin D3 is ineffective for reducing depression severity. Cognitive behavioral therapy (CBT) is more effective than (undefined) psychotherapy and placebo for depression improvement and quality of life (low SOE), and acupressure is more effective than treatment as usual (TAU) or sham to reduce depression severity (low SOE). CONCLUSION: There is limited research evaluating the diagnostic accuracy of most screening tools for depression in patients with ESRD. The BDI-II with a cutoff of ≥16 provides a good balance of sensitivity and specificity. More research is needed to support the use of other tools. We found low SOE that CBT, sertraline, and acupressure may be beneficial. There is moderate SOE that high-dose Vitamin D3 is ineffective. More research is needed.
Subject Depression, Mental -- Diagnosis -- United States.
Depression, Mental -- Treatment -- United States.
Chronic renal failure -- United States.
Veterans -- Medical care -- United States.
Depressive Disorder -- diagnosis
Depression -- diagnosis
Kidney Failure, Chronic -- complications
Mass Screening -- methods
Depressive Disorder -- therapy
Depression -- therapy
Comparative Effectiveness Research
Dépression -- Diagnostic -- États-Unis.
Dépression -- Traitement -- États-Unis.
Insuffisance rénale chronique -- États-Unis.
Anciens combattants -- Soins médicaux -- États-Unis.
Chronic renal failure. (OCoLC)fst00860126
Depression, Mental -- Diagnosis. (OCoLC)fst00890938
Depression, Mental -- Treatment. (OCoLC)fst00890967
Veterans -- Medical care. (OCoLC)fst01165761
United States. (OCoLC)fst01204155 https://id.oclc.org/worldcat/entity/E39PBJtxgQXMWqmjMjjwXRHgrq
Genre/Form Systematic Review
Revues systématiques.
Added Author United States. Department of Veterans Affairs. Health Services Research and Development Service, issuing body.
Running Title ESRD and depression
Standard No. NLM 101775023
AU@ 000075631869
Gpo Item No. 0985-A-12 (online)
Sudoc No. VA 1.107/3:R 29

 
    
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