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Author Mokra, Daniela, author.

Title Acute lung injury : epidemiology, health effects and therapeutic treatment strategies / Daniela Mokrá.

Publication Info. New York, New York : Nova Science Publishers, Inc., 2014.
©2014

Copies

Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource (98 pages) : illustrations.
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Pulmonary and Respiratory Diseases and Disorders
Pulmonary and Respiratory Diseases and Disorders.
Bibliography Includes bibliographical references and index.
Note Print version record.
Contents ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion.
ConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References.
Chapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration.
Surfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index.
Summary In this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in.
Subject Respiratory distress syndrome, Adult -- Congresses.
Respiratory intensive care -- Congresses.
Lungs -- Wounds and injuries -- Congresses.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Lungs -- Wounds and injuries. (OCoLC)fst01003864
Respiratory distress syndrome, Adult. (OCoLC)fst01095734
Respiratory intensive care. (OCoLC)fst01095755
Genre/Form Electronic books.
Conference papers and proceedings. (OCoLC)fst01423772
Other Form: Print version: Mokrá, Daniela. Acute lung injury : epidemiology, health effects and therapeutic treatment strategies. New York, New York : Nova Science Publishers, Inc., ©2014 ix, 86 pages Pulmonary and Respiratory Diseases and Disorders 9781614704263
ISBN 9781633218697 (electronic bk.)
1633218694 (electronic bk.)
9781614704263
Standard No. DEBBG BV042793278

 
    
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