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Author Simpson, A. Hamish R. W., author.

Title Experimental research methods in orthopedics and trauma / Hamish Simpson, Peter Augat.

Publication Info. Stuttgart ; New York : Thieme, [2015]


Location Call No. OPAC Message Status
 Axe EBSCO Clinical Nursing E-Book  Electronic Book    ---  Available
Description 1 online resource (xvii, 446 pages) : illustrations
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Note Print version record.
Bibliography Includes bibliographica references and index.
Contents Experimental Research Methods in Orthopedics and Trauma; Title Page; Copyright; Contents; Foreword; Endorsement by the International Combined Orthopaedic Research Societies (I-CORS) Member Organizations; Preface; Acknowledgments; Contributors; 1 Why Do We Need Experimental Research?; 1 Evidence-Based Research; 2 Establishing a Basic Research Facility in Orthopedic Surgery; 3 Good Laboratory Practice and Quality Control; 4 How to Prepare for a Period in Research; 2 Structural Biomechanics; 5 Physiological Boundary Conditions for Mechanical Testing.
6 Static, Dynamic, and Fatigue Mechanical Testing7 Use of Human and Animal Specimens in Biomechanical Testing; 8 Whole Bone Biomechanics; 9 Biomechanics of Trabecular and Cortical Bone; 10 Biomechanics of Fracture Fixation; 11 Biomechanical Assessment of Fracture Repair; 12 Biomechanics of Cartilage; 13 Biomechanics of Joints; 14 Spine Biomechanics; 3 Functional Biomechanics; 15 Musculokeletal Dynamics; 16 Measurement Techniques; 17 Clinical Assessment of Function; 18 Functional Biomechanics with Cadaver Specimens; 4 Numerical Biomechanics; 19 Inverse Dynamics.
20 Principles of Finite Elements Analysis21 Validation of Finite Element Models; 22 Computational Biomechanics of Bone; 23 Numerical Simulation of Implants and Prosthetic Devices; 24 Numerical Simulation of Fracture Healing and Bone Remodelling; 5 Imaging; 25 Micro-Computed Tomography Imaging of Bone Tissue; 26 Imaging Bone; 27 Ultrasound Techniques for Imaging Bone; 28 In Vivo Scanning; 29 Imaging of Cartilage Function; 30 Histochemistry Bone and Cartilage; 31 Immunohistochemistry; 32 Molecular Imaging In Situ Hybridization; 33 Laser Scanning Confocal Microscopy and Laser Microdissection.
34 Image Analysis Histomorphometry Stereology6 Cellular Studies; 35 Cell Culture Research; 36 Cartilage Explants and Organ Culture Models; 37 Fluid Flow and Strain in Bone; 38 Biomechanics of Bone Cells; 7 Molecular Techniques in Bone Repair; 39 Molecular Testing; 40 Genetically Modified Models for Bone Repair; 8 In Vivo Models; 41 General Considerations for an In Vivo Model; 42 Animal Models for Bone Healing; 43 Models for Impaired Healing; 44 In Vivo Models for Bone and Joint Infections; 45 In Vivo Models for Articular Cartilage Repair; 46 In Vivo Soft Tissue Models; 9 Tissue Engineering.
47 Scaffolds for Tissue Engineering and Materials for Repair48 Use of Growth Factors in Musculoskeletal Research; 49 Stem Cells for Musculoskeletal Repair; 50 Biological Evaluation and Testing of Medical Devices; 10 Statistics for Experimental Research; 51 Study Design; 52 Power and Sample Size Calculation; 53 Nonparametric versus Parametric Tests; 54 How to Limit Bias in Experimental Research; Index.
Summary From bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this roadmap at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. Special Features: Utilizes the principles and methodology of modern, evidence-bas.
Language English.
Subject Musculoskeletal system -- Wounds and injuries.
Orthopedics -- Research.
Orthopedic emergencies.
Emergency medicine.
Musculoskeletal system -- Diseases.
Biomedical Research
Orthopedics -- methods
Biomechanical Phenomena
Musculoskeletal Diseases
Orthopedic Procedures -- methods
Emergency Medicine
Appareil locomoteur -- Lésions et blessures.
Orthopédie -- Recherche.
Urgences en orthopédie.
Médecine d'urgence.
Appareil locomoteur -- Maladies.
MEDICAL -- Surgery -- General.
Musculoskeletal system -- Diseases. (OCoLC)fst01030019
Emergency medicine. (OCoLC)fst00908615
Musculoskeletal system -- Wounds and injuries. (OCoLC)fst01030036
Orthopedic emergencies. (OCoLC)fst01048544
Orthopedics -- Research. (OCoLC)fst01048571
Genre/Form Electronic books.
Electronic books.
Added Author Augat, Peter, author.
Other Form: Print version: Simpson, A. Hamish R.W. Experimental research methods in orthopedics and trauma 9783131731111 (DLC) 2014019935 (OCoLC)880685394
ISBN 9783131731210 (electronic bk.)
3131731214 (electronic bk.)
Standard No. AU@ 000055221565
DEBBG BV043958882
DEBSZ 481291083
DKDLA 820120-katalog:999940706505765

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