| Description |
1 online resource (xvii, 446 pages) : illustrations |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Note |
Print version record. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Experimental Research Methods in Orthopedics and Trauma; Title Page; Copyright; Contents; Foreword; Endorsement by the International Combined Orthopaedic Research Societies (I-CORS) Member Organizations; Preface; Acknowledgments; Contributors; 1 Why Do We Need Experimental Research?; 1 Evidence-Based Research; 2 Establishing a Basic Research Facility in Orthopedic Surgery; 3 Good Laboratory Practice and Quality Control; 4 How to Prepare for a Period in Research; 2 Structural Biomechanics; 5 Physiological Boundary Conditions for Mechanical Testing. |
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6 Static, Dynamic, and Fatigue Mechanical Testing7 Use of Human and Animal Specimens in Biomechanical Testing; 8 Whole Bone Biomechanics; 9 Biomechanics of Trabecular and Cortical Bone; 10 Biomechanics of Fracture Fixation; 11 Biomechanical Assessment of Fracture Repair; 12 Biomechanics of Cartilage; 13 Biomechanics of Joints; 14 Spine Biomechanics; 3 Functional Biomechanics; 15 Musculokeletal Dynamics; 16 Measurement Techniques; 17 Clinical Assessment of Function; 18 Functional Biomechanics with Cadaver Specimens; 4 Numerical Biomechanics; 19 Inverse Dynamics. |
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20 Principles of Finite Elements Analysis21 Validation of Finite Element Models; 22 Computational Biomechanics of Bone; 23 Numerical Simulation of Implants and Prosthetic Devices; 24 Numerical Simulation of Fracture Healing and Bone Remodelling; 5 Imaging; 25 Micro-Computed Tomography Imaging of Bone Tissue; 26 Imaging Bone; 27 Ultrasound Techniques for Imaging Bone; 28 In Vivo Scanning; 29 Imaging of Cartilage Function; 30 Histochemistry Bone and Cartilage; 31 Immunohistochemistry; 32 Molecular Imaging In Situ Hybridization; 33 Laser Scanning Confocal Microscopy and Laser Microdissection. |
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34 Image Analysis Histomorphometry Stereology6 Cellular Studies; 35 Cell Culture Research; 36 Cartilage Explants and Organ Culture Models; 37 Fluid Flow and Strain in Bone; 38 Biomechanics of Bone Cells; 7 Molecular Techniques in Bone Repair; 39 Molecular Testing; 40 Genetically Modified Models for Bone Repair; 8 In Vivo Models; 41 General Considerations for an In Vivo Model; 42 Animal Models for Bone Healing; 43 Models for Impaired Healing; 44 In Vivo Models for Bone and Joint Infections; 45 In Vivo Models for Articular Cartilage Repair; 46 In Vivo Soft Tissue Models; 9 Tissue Engineering. |
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47 Scaffolds for Tissue Engineering and Materials for Repair48 Use of Growth Factors in Musculoskeletal Research; 49 Stem Cells for Musculoskeletal Repair; 50 Biological Evaluation and Testing of Medical Devices; 10 Statistics for Experimental Research; 51 Study Design; 52 Power and Sample Size Calculation; 53 Nonparametric versus Parametric Tests; 54 How to Limit Bias in Experimental Research; Index. |
| Summary |
From bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this roadmap at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. Special Features: Utilizes the principles and methodology of modern, evidence-bas. |
| Language |
English. |
| Subject |
Musculoskeletal system -- Wounds and injuries.
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Orthopedics -- Research.
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Orthopedic emergencies.
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Emergency medicine.
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Musculoskeletal system -- Diseases.
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Biomedical Research |
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Orthopedics -- methods |
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Emergency Medicine |
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Biomechanical Phenomena |
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Musculoskeletal Diseases |
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Orthopedic Procedures -- methods |
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Appareil locomoteur -- Lésions et blessures.
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Orthopédie -- Recherche.
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Urgences en orthopédie.
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Médecine d'urgence.
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Appareil locomoteur -- Maladies.
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medicines (material)
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MEDICAL -- Surgery -- General.
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Musculoskeletal system -- Diseases
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Emergency medicine
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Musculoskeletal system -- Wounds and injuries
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Orthopedic emergencies
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Orthopedics -- Research
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| Genre/Form |
Internet Resources.
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| Added Author |
Augat, Peter, author.
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| Other Form: |
Print version: Simpson, A. Hamish R.W. Experimental research methods in orthopedics and trauma 9783131731111 (DLC) 2014019935 (OCoLC)880685394 |
| ISBN |
9783131731210 (electronic bk.) |
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3131731214 (electronic bk.) |
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9783131731111 |
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3131731117 |
| Standard No. |
10.1055/b-003-121999. doi |
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AU@ 000055221565 |
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DEBBG BV043958882 |
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DEBSZ 481291083 |
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